Literature DB >> 2083068

Vanadate-induced intracellular calcium elevation in the stria vascularis of the guinea pig: fluorescence ratio imaging microscopy.

K Ikeda1, Y Saito, T Takasaka.   

Abstract

Cytoplasmic free calcium has been observed in fura 2-loaded stria vascularis of the guinea pig. Following the application of vanadate, the cytosolic Ca2+ concentration increased by 45%. Complete substitution of extracellular Na+ with N-methyl D-glucamine did not alter the free calcium concentration. These findings suggest that the Ca2+ transport in the stria vascularis is mediated by a Ca2(+)-ATPase enzyme mechanism rather than Na(+)-Ca2+ exchange.

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Year:  1990        PMID: 2083068     DOI: 10.1007/BF00634775

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  9 in total

Review 1.  Na-Ca exchange: stoichiometry and electrogenicity.

Authors:  D A Eisner; W J Lederer
Journal:  Am J Physiol       Date:  1985-03

2.  Electrochemical profile for calcium ions in the stria vascularis: cellular model of calcium transport mechanism.

Authors:  K Ikeda; T Morizono
Journal:  Hear Res       Date:  1989-06-15       Impact factor: 3.208

3.  The Ca2+ activity of cochlear endolymph of the guinea pig and the effect of inhibitors.

Authors:  K Ikeda; J Kusakari; T Takasaka; Y Saito
Journal:  Hear Res       Date:  1987       Impact factor: 3.208

Review 4.  Intracellular calcium homeostasis.

Authors:  E Carafoli
Journal:  Annu Rev Biochem       Date:  1987       Impact factor: 23.643

Review 5.  Sodium-calcium exchange in plasma membrane vesicles.

Authors:  K D Philipson
Journal:  Annu Rev Physiol       Date:  1985       Impact factor: 19.318

6.  A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Authors:  G Grynkiewicz; M Poenie; R Y Tsien
Journal:  J Biol Chem       Date:  1985-03-25       Impact factor: 5.157

7.  Very low calcium content of cochlear endolymph, an extracellular fluid.

Authors:  S K Bosher; R L Warren
Journal:  Nature       Date:  1978-06-01       Impact factor: 49.962

8.  Mechano-electrical transduction currents in isolated vestibular hair cells of the chick.

Authors:  H Ohmori
Journal:  J Physiol       Date:  1985-02       Impact factor: 5.182

9.  Calcium transport mechanism in the endolymph of the chinchilla.

Authors:  K Ikeda; T Morizono
Journal:  Hear Res       Date:  1988-08       Impact factor: 3.208

  9 in total

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