Literature DB >> 20830538

HIV and bone loss.

Shitij Arora1, Manasi Agrawal, Li Sun, Frantz Duffoo, Mone Zaidi, Jameel Iqbal.   

Abstract

The use of antiretroviral therapy has significantly reduced the number of deaths due to HIV/AIDS. However, no current therapy can suppress the virus completely, and as the HIV-infected population continues to live longer new complications are emerging from the persistence of the virus and use of antiretroviral therapy. This review summarizes the clinical evidence linking HIV-associated osteoporosis to direct infection and antiretroviral therapy (ART) use. The purported molecular mechanisms involved in bone loss are also reviewed. Additionally, recommendations regarding the pharmacologic management of HIV/ART-related osteoporosis are given.

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Year:  2010        PMID： 20830538     DOI： 10.1007/s11914-010-0036-x

Source DB:  PubMed          Journal:  Curr Osteoporos Rep        ISSN： 1544-1873            Impact factor:   5.096


  46 in total

Review 1.  Metabolic bone disease in HIV infection.

Authors:  Marco Borderi; Davide Gibellini; Fabio Vescini; Elisa De Crignis; Laura Cimatti; Carlo Biagetti; Livia Tampellini; Maria C Re
Journal:  AIDS       Date:  2009-07-17       Impact factor: 4.177

2.  Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis.

Authors:  J L Martin; C E Brown; N Matthews-Davis; J E Reardon
Journal:  Antimicrob Agents Chemother       Date:  1994-12       Impact factor: 5.191

3.  Down-regulation of osteoprotegerin production in bone marrow macrophages by macrophage colony-stimulating factor.

Authors:  Naoko Yamada; Tohru Tsujimura; Haruyasu Ueda; Shin-Ichi Hayashi; Hideki Ohyama; Haruki Okamura; Nobuyuki Terada
Journal:  Cytokine       Date:  2005-08-21       Impact factor: 3.861

4.  Osteopenia in HIV-infected men: association with asymptomatic lactic acidemia and lower weight pre-antiretroviral therapy.

Authors:  A Carr; J Miller; J A Eisman; D A Cooper
Journal:  AIDS       Date:  2001-04-13       Impact factor: 4.177

5.  Evaluation of hypophosphataemia in tenofovir disoproxil fumarate (TDF)-exposed and TDF-unexposed HIV-infected out-patients receiving highly active antiretroviral therapy.

Authors:  K Buchacz; J T Brooks; T Tong; A C Moorman; R K Baker; S D Holmberg; A Greenberg
Journal:  HIV Med       Date:  2006-10       Impact factor: 3.180

6.  Tenofovir DF in antiretroviral-experienced patients: results from a 48-week, randomized, double-blind study.

Authors:  Robert T Schooley; Peter Ruane; Robert A Myers; Gildon Beall; Harry Lampiris; Daniel Berger; Shan-Shan Chen; Michael D Miller; Erica Isaacson; Andrew K Cheng
Journal:  AIDS       Date:  2002-06-14       Impact factor: 4.177

7.  Decreased bone mineral density and increased fracture risk in aging men with or at risk for HIV infection.

Authors:  Julia H Arnsten; Ruth Freeman; Andrea A Howard; Michelle Floris-Moore; Yungtai Lo; Robert S Klein
Journal:  AIDS       Date:  2007-03-12       Impact factor: 4.177

8.  Hyperlactataemia and lactic acidosis during antiretroviral therapy: relevance, reproducibility and possible risk factors.

Authors:  Graeme J Moyle; Debasis Datta; Sundhiya Mandalia; John Morlese; David Asboe; Brian G Gazzard
Journal:  AIDS       Date:  2002-07-05       Impact factor: 4.177

9.  WNT/beta-catenin signaling is involved in regulation of osteoclast differentiation by human immunodeficiency virus protease inhibitor ritonavir: relationship to human immunodeficiency virus-linked bone mineral loss.

Authors:  Rozbeh Modarresi; Zhaoying Xiang; Michael Yin; Jeffrey Laurence
Journal:  Am J Pathol       Date:  2008-12-18       Impact factor: 4.307

Review 10.  Macrophage colony-stimulating factor in the pathogenesis of HIV infection: potential target for therapeutic intervention.

Authors:  Valerie Haine; Tracy Fischer-Smith; Jay Rappaport
Journal:  J Neuroimmune Pharmacol       Date:  2006-03       Impact factor: 4.147
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  12 in total

1.  Bone disease in HIV infection.

Authors:  Maristella Francesca Saccomanno; Adriana Ammassari
Journal:  Clin Cases Miner Bone Metab       Date:  2011-01

2.  A novel library screen identifies immunosuppressors that promote osteoblast differentiation.

Authors:  Ariana Darcy; Micah Meltzer; Joseph Miller; Steven Lee; Scott Chappell; Kris Ver Donck; Monty Montano
Journal:  Bone       Date:  2012-03-13       Impact factor: 4.398

3.  Comorbidities associated with HIV and antiretroviral therapy (clinical sciences): a workshop report.

Authors:  L T Vernon; Plp Jayashantha; M M Chidzonga; M C Komesu; R G Nair; N W Johnson
Journal:  Oral Dis       Date:  2016-04       Impact factor: 3.511

Review 4.  Nucleotide Reverse Transcriptase Inhibitors: A Thorough Review, Present Status and Future Perspective as HIV Therapeutics.

Authors:  Ashley D Holec; Subhra Mandal; Pavan Kumar Prathipati; Christopher J Destache
Journal:  Curr HIV Res       Date:  2017       Impact factor: 1.581

Review 5.  HIV infection and osteoporosis: pathophysiology, diagnosis, and treatment options.

Authors:  Micol S Rothman; Mary T Bessesen
Journal:  Curr Osteoporos Rep       Date:  2012-12       Impact factor: 5.096

6.  Brief Report: Macrophage Activation in HIV-Infected Adolescent Males Contributes to Differential Bone Loss by Sex: Adolescent Trials Network Study 021.

Authors:  Alexandra Ruan; Nicole H Tobin; Kathleen Mulligan; Adrienne Rollie; Fan Li; John Sleasman; Grace M Aldrovandi
Journal:  J Acquir Immune Defic Syndr       Date:  2016-08-01       Impact factor: 3.731

7.  Antiretroviral therapy induces a rapid increase in bone resorption that is positively associated with the magnitude of immune reconstitution in HIV infection.

Authors:  Ighovwerha Ofotokun; Kehmia Titanji; Aswani Vunnava; Susanne Roser-Page; Tatyana Vikulina; Francois Villinger; Kenneth Rogers; Anandi N Sheth; Cecile Delille Lahiri; Jeffrey L Lennox; M Neale Weitzmann
Journal:  AIDS       Date:  2016-01-28       Impact factor: 4.177

8.  Homeostatic Expansion of CD4+ T Cells Promotes Cortical and Trabecular Bone Loss, Whereas CD8+ T Cells Induce Trabecular Bone Loss Only.

Authors:  M Neale Weitzmann; Tatyana Vikulina; Susanne Roser-Page; Masayoshi Yamaguchi; Ighovwerha Ofotokun
Journal:  J Infect Dis       Date:  2017-11-27       Impact factor: 5.226

9.  Osteoimmunopathology in HIV/AIDS: A Translational Evidence-Based Perspective.

Authors:  André Barkhordarian; Reem Ajaj; Manisha H Ramchandani; Gary Demerjian; Riana Cayabyab; Sohrab Danaie; Nora Ghodousi; Natasha Iyer; Nicole Mahanian; Linda Phi; Amy Giroux; Ercolano Manfrini; Negoita Neagos; Muniza Siddiqui; Olivia S Cajulis; Xenia M C Brant; Paul Shapshak; Francesco Chiappelli
Journal:  Patholog Res Int       Date:  2011-05-21

10.  Osteopenia and osteoporosis in people living with HIV: multiprofessional approach.

Authors:  Ana Lucia Lei Munhoz Lima; Priscila Rosalba D de Oliveira; Perola Grimberg Plapler; Flora Maria D Andrea Marcolino; Eduardo de Souza Meirelles; André Sugawara; Riccardo Gomes Gobbi; Alexandre Leme Godoy Dos Santos; Gilberto Luis Camanho
Journal:  HIV AIDS (Auckl)       Date:  2011-12-08
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