Literature DB >> 20830245

Primary lung seminoma in a 76-year-old man: a case report.

Shaojun Zhu1, Yanhong Li, Guiqiu Liu, Xiujuan Han, Li Gong, Li Yao, Miao Lan, Wei Zhang.   

Abstract

BACKGROUND: Seminoma is a rare event in old male population. In this report, we present a rare case of primary seminoma in the lung of a 76-years-old man. CASE
PRESENTATION: The patient was a 76-year-old man admitted with respiratory tract symptom and hemoptysis. The Chest Routine Scan and CT showed there was a consolidation area in the basal segments at the lower lobe of left lung. Bronchoscope also exhibited a neoplasm in left lung. During left lower lobectomy, we found that adherence occurred widely in left thoracic wall, and the pleural membrane was shrinkage. No chemotherapy or radiotherapy was given. Patient was died at 140 days after the surgery mainly due to the dyscrasia and secondary seminoma in left 7th to 9th ribs. Placental alkaline phosphatase (PLAP) and CD117 were found to be positive with immunohistochemical studies. Along with other evidences, this case was identified as the manifestations of seminoma.
CONCLUSION: Although primary seminoma of the lung is rare in old male population, the diagnosis should be taken into serious consideration in order to improve the treatment. And in this case, primary lung seminoma is associated with high degree of malignancy and metastasis.

Entities:  

Keywords:  Seminoma; immunohistochemistry; lung

Mesh:

Year:  2010        PMID: 20830245      PMCID: PMC2933394     

Source DB:  PubMed          Journal:  Int J Clin Exp Pathol        ISSN: 1936-2625


  14 in total

1.  Increase in testicular cancer incidence in six European countries: a birth cohort phenomenon.

Authors:  R Bergström; H O Adami; M Möhner; W Zatonski; H Storm; A Ekbom; S Tretli; L Teppo; O Akre; T Hakulinen
Journal:  J Natl Cancer Inst       Date:  1996-06-05       Impact factor: 13.506

2.  Malignant testicular tumours in Finland.

Authors:  L Teppo
Journal:  Acta Pathol Microbiol Scand       Date:  1969

3.  Improved chemotherapy in disseminated testicular cancer.

Authors:  L H Einhorn; J P Donohue
Journal:  J Urol       Date:  1977-01       Impact factor: 7.450

4.  The differential diagnosis of testicular germ cell tumors in theory and practice. A critical analysis of two major systems of classifiction and review of 389 cases.

Authors:  A R von Hochstetter; C E Hedinger
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1982-08

5.  Extragonadal germ cell tumors in Taiwan: an analysis of treatment results of 59 patients.

Authors:  Yu-Juei Hsu; Lu Pai; Yeu-Chin Chen; Ching-Liang Ho; Woei-Yau Kao; Tsu-Yi Chao
Journal:  Cancer       Date:  2002-08-15       Impact factor: 6.860

6.  Primary mediastinal seminoma.

Authors:  C Pugliese; G Michetti; R Villa; M Bamberga; R Alesina; M Cottini; E Pezzica; T Motta
Journal:  Monaldi Arch Chest Dis       Date:  1994-12

7.  Testicular germ cell tumours in Denmark 1976-1980. Pathology of 1058 consecutive cases.

Authors:  G Krag Jacobsen; H Barlebo; J Olsen; H P Schultz; H Starklint; H Søgaard; M Vaeth
Journal:  Acta Radiol Oncol       Date:  1984

8.  Trends in the incidence of testicular germ cell tumors in the United States.

Authors:  Katherine A McGlynn; Susan S Devesa; Alice J Sigurdson; Linda M Brown; Lilian Tsao; Robert E Tarone
Journal:  Cancer       Date:  2003-01-01       Impact factor: 6.860

Review 9.  An overview of testicular germ cell tumors.

Authors:  Armita Bahrami; Jae Y Ro; Alberto G Ayala
Journal:  Arch Pathol Lab Med       Date:  2007-08       Impact factor: 5.534

10.  Continuing increase in incidence of germ-cell testis cancer in young adults: experience from Connecticut, USA, 1935-1992.

Authors:  T Zheng; T R Holford; Z Ma; B A Ward; J Flannery; P Boyle
Journal:  Int J Cancer       Date:  1996-03-15       Impact factor: 7.396

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