Literature DB >> 20829800

Economic impact of the clinical benefits of bariatric surgery in diabetes patients with BMI ≥35 kg/m².

Samuel Klein1, Arindam Ghosh, Pierre Y Cremieux, Sara Eapen, Tamara J McGavock.   

Abstract

The medical costs for a type 2 diabetes patient are two to four times greater than the costs for a patient without diabetes. Bariatric surgery is the most effective weight-loss therapy and has marked therapeutic effects on diabetes. We estimate the economic effect of the clinical benefits of bariatric surgery for diabetes patients with BMI ≥ 35 kg/m². Using an administrative claims database of privately insured patients covering 8.5 million lives 1999-2007, we identify obese patients with diabetes, aged 18-65 years, who were treated with bariatric surgery identified using Healthcare Common Procedure Coding System codes. These patients were matched with nonsurgery control patients on demographic factors, comorbidities, and health-care costs. The overall return on investment (RoI) associated with bariatric surgery was calculated using multivariate analysis. Surgery and control patients were compared postindex with respect to diagnostic claims for diabetes, diabetes medication claims, and adjusted diabetes medication and supply costs. Surgery costs were fully recovered after 26 months for laparoscopic surgery. At month 6, 28% of surgery patients had a diabetes diagnosis, compared to 74% of control patients (P < 0.001). Among preindex insulin users, insulin use dropped to 43% by month 3 for surgery patients, vs. 84% for controls (P < 0.001). By month 1, medication and supply costs were significantly lower for surgery patients (P < 0.001). The therapeutic benefits of bariatric surgery on diabetes translate into considerable economic benefits. These data suggest that surgical therapy is clinically more effective and ultimately less expensive than standard therapy for diabetes patients with BMI ≥ 35 kg/m².

Entities:  

Mesh:

Substances:

Year:  2010        PMID: 20829800      PMCID: PMC3721344          DOI: 10.1038/oby.2010.199

Source DB:  PubMed          Journal:  Obesity (Silver Spring)        ISSN: 1930-7381            Impact factor:   5.002


  20 in total

1.  Gastric bypass surgery in severely obese type 1 diabetic patients.

Authors:  Leszek Czupryniak; Janusz Strzelczyk; Katarzyna Cypryk; Maciej Pawlowski; Dariusz Szymanski; Andrzej Lewinski; Jerzy Loba
Journal:  Diabetes Care       Date:  2004-10       Impact factor: 19.112

2.  Clinical outcomes and adherence to medications measured by claims data in patients with diabetes.

Authors:  Manel Pladevall; L Keoki Williams; Lisa Ann Potts; George Divine; Hugo Xi; Jennifer Elston Lafata
Journal:  Diabetes Care       Date:  2004-12       Impact factor: 19.112

3.  Outcomes after laparoscopic Roux-en-Y gastric bypass for morbid obesity.

Authors:  P R Schauer; S Ikramuddin; W Gourash; R Ramanathan; J Luketich
Journal:  Ann Surg       Date:  2000-10       Impact factor: 12.969

4.  Long-term effects of modest weight loss in type II diabetic patients.

Authors:  R R Wing; R Koeske; L H Epstein; M P Nowalk; W Gooding; D Becker
Journal:  Arch Intern Med       Date:  1987-10

5.  Weight change and diabetes incidence: findings from a national cohort of US adults.

Authors:  E S Ford; D F Williamson; S Liu
Journal:  Am J Epidemiol       Date:  1997-08-01       Impact factor: 4.897

6.  Weight gain as a risk factor for clinical diabetes mellitus in women.

Authors:  G A Colditz; W C Willett; A Rotnitzky; J E Manson
Journal:  Ann Intern Med       Date:  1995-04-01       Impact factor: 25.391

7.  Prompt reduction in use of medications for comorbid conditions after bariatric surgery.

Authors:  Jodi B Segal; Jeanne M Clark; Andrew D Shore; Francesca Dominici; Thomas Magnuson; Thomas M Richards; Jonathan P Weiner; Eric B Bass; Albert W Wu; Martin A Makary
Journal:  Obes Surg       Date:  2009-12       Impact factor: 4.129

8.  The effect of Roux-en-Y gastric bypass on prescription drug costs.

Authors:  L Lamar Snow; L Steve Weinstein; Jeffrey K Hannon; Daniel R Lane; Forrest G Ringold; Peggy A Hansen; Michael D Pointer
Journal:  Obes Surg       Date:  2004-09       Impact factor: 4.129

9.  Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus.

Authors:  W J Pories; M S Swanson; K G MacDonald; S B Long; P G Morris; B M Brown; H A Barakat; R A deRamon; G Israel; J M Dolezal
Journal:  Ann Surg       Date:  1995-09       Impact factor: 12.969

10.  Pharmaceutical savings after gastric bypass surgery.

Authors:  John S Monk; Nancy Dia Nagib; Wolfgang Stehr
Journal:  Obes Surg       Date:  2004-01       Impact factor: 4.129

View more
  24 in total

1.  Impact of bariatric surgery on health care utilization and costs among patients with diabetes.

Authors:  Sara N Bleich; Hsien-Yen Chang; Bryan Lau; Kimberly Steele; Jeanne M Clark; Thomas Richards; Jonathan P Weiner; Albert W Wu; Jodi B Segal
Journal:  Med Care       Date:  2012-01       Impact factor: 2.983

2.  Impact of bariatric surgery on the medical management and costs of obese patients in France: an analysis of a national representative claims database.

Authors:  Sébastien Czernichow; David Moszkowicz; Karine Szwarcensztein; Corinne Emery; Antoine Lafuma; Julie Gourmelen; Francis Fagnani
Journal:  Obes Surg       Date:  2015-06       Impact factor: 4.129

3.  The Socio-economic Impact of Bariatric Surgery.

Authors:  Arendse Tange Larsen; Betina Højgaard; Rikke Ibsen; Jakob Kjellberg
Journal:  Obes Surg       Date:  2018-02       Impact factor: 4.129

4.  Nationwide Macroeconomic Variables and the Growth Rate of Bariatric Surgeries in Brazil.

Authors:  Everton Cazzo; Almino Cardoso Ramos; José Carlos Pareja; Elinton Adami Chaim
Journal:  Obes Surg       Date:  2018-10       Impact factor: 4.129

5.  Obesity: health economics of bariatric surgery--benefit versus cost.

Authors:  John Dixon
Journal:  Nat Rev Endocrinol       Date:  2012-09-11       Impact factor: 43.330

Review 6.  Influence of bariatric surgery on the use and pharmacokinetics of some major drug classes.

Authors:  Jan Peter Yska; Susanne van der Linde; Véronique V Tapper; Jan A Apers; Marloes Emous; Erik R Totté; Bob Wilffert; Eric N van Roon
Journal:  Obes Surg       Date:  2013-06       Impact factor: 4.129

Review 7.  Evidence Base for Optimal Preoperative Preparation for Bariatric Surgery: Does Mandatory Weight Loss Make a Difference?

Authors:  Julie J Kim
Journal:  Curr Obes Rep       Date:  2017-09

8.  Medical research: Time to think differently about diabetes.

Authors:  Francesco Rubino
Journal:  Nature       Date:  2016-05-26       Impact factor: 49.962

9.  Bariatric surgery as a treatment option in patients with type 2 diabetes mellitus.

Authors:  Marianna Spanou; Konstantinos Tziomalos
Journal:  World J Diabetes       Date:  2013-04-15

10.  Bariatric surgery in the era of personalized medicine.

Authors:  Andrew A Butler; Robert W O'Rourke
Journal:  Gastroenterology       Date:  2013-01-21       Impact factor: 22.682

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.