Literature DB >> 20828911

Hyperplasia of the mandibular condyle: clinical, histopathologic, and treatment considerations in a series of 36 patients.

Laura Villanueva-Alcojol1, Florencio Monje, Raúl González-García.   

Abstract

PURPOSE: Mandibular condylar hyperplasia (CH) is a rare entity that causes overdevelopment of the mandible, creating functional and esthetic problems. The aim of this article was to describe demographic and clinical characteristics of CH, analyze histopathologic features and their association with scintigraphic and clinical findings, and evaluate esthetic and functional results after treatment by high condylectomy during the active phase.
MATERIALS AND METHODS: This retrospective study included 36 patients whose condyles were removed because of excessive unilateral growth resulting in facial asymmetry and occlusal disturbance. Of the 36 patients, 13 had had symptoms related to the temporomandibular joint, such as pain or clicking. In all the cases, high condylectomy was performed, and surgical specimens were sent for histologic examination and divided into 4 histologic types as described by Slootweg and Müller. Statistical analysis was performed by use of R software (version 2.10.1; R Foundation for Statistical Computing, Vienna, Austria) and SPSS software for Windows (version 15.0; SPSS, Chicago, IL) to evaluate our results. A χ(2) test was carried out to assess the possible association between gender and involved side. The association of histologic appearance with clinical symptoms was estimated by use of the Fisher exact test. An analysis of variance test was performed to evaluate a possible association between patient age and histologic type according to the Slootweg and Müller classification and between histologic type and uptake on bone single photon emission computed tomography (SPECT).
RESULTS: We could not find a relationship between histologic type and uptake of the affected condyle on bone SPECT or between age and histologic type. However, our statistical analysis revealed an association between histologic appearance and the presence of joint symptoms (P = .0049). Clinically, occlusion and facial symmetry improved in all patients postoperatively, and no recurrence was noted in any patient. Six patients required secondary surgery.
CONCLUSION: We could not find any significant association between age and histologic type or between bone SPECT and histologic type. However, a significant association between histologic type and temporomandibular joint symptoms was observed. High condylectomy combined with orthodontics achieved optimal esthetic and functional results and constituted the unique and definitive treatment in 30 of 36 patients. Copyright Â
© 2011 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20828911     DOI: 10.1016/j.joms.2010.04.025

Source DB:  PubMed          Journal:  J Oral Maxillofac Surg        ISSN: 0278-2391            Impact factor:   1.895


  13 in total

Review 1.  Mandible condylar hyperplasia: a review of diagnosis and treatment protocol.

Authors:  Sergio Olate; Henrique Duque Netto; Jaime Rodriguez-Chessa; Juan Pablo Alister; Jose de Albergaria-Barbosa; Márcio de Moraes
Journal:  Int J Clin Exp Med       Date:  2013-09-25

2.  TMJ function after partial condylectomy in active mandibular condylar hyperplasia.

Authors:  Sergio Olate; Felipe Martinez; Francisca Uribe; Leandro Pozzer; Lucas Cavalieri-Pereira; Marcio de Moraes
Journal:  Int J Clin Exp Med       Date:  2014-03-15

3.  ANKH Polymorphisms and Clicking of the Temporomandibular Joint in Dental Residents.

Authors:  Boyen Huang; Katsu Takahashi; Tomoko Goto; Honoka Kiso; Manabu Sugai; Akira Shimizu; Shinji Kosugi; Kazuhisa Bessho
Journal:  J Maxillofac Oral Surg       Date:  2014-05-29

4.  Proximity of the maxillary artery to the neck of the mandibular condyle: anatomical study.

Authors:  Francisco Paulo Araújo Maia; Gilberto Cunha de Sousa Filho; Fernando Augusto Pacífico; Lucas Carvalho Aragão Albuquerque; Amanda Freire de Melo Vasconcelos; Belmiro Cavalcanti do Egito Vasconcelos
Journal:  Oral Maxillofac Surg       Date:  2019-07-05

5.  Condylar hyperplasia: An updated review of the literature.

Authors:  Luis Eduardo Almeida; Joseph Zacharias; Sean Pierce
Journal:  Korean J Orthod       Date:  2015-11-20       Impact factor: 1.372

6.  Facial asymmetry and condylar hyperplasia: considerations for diagnosis in 27 consecutives patients.

Authors:  Sergio Olate; Andrés Almeida; Juan Pablo Alister; Pablo Navarro; Henrique Duque Netto; Márcio de Moraes
Journal:  Int J Clin Exp Med       Date:  2013-10-25

7.  A Better Understanding of Unilateral Condylar Hyperplasia of the Mandible.

Authors:  Jaime Gateno; Kevin B Coppelson; Tianshu Kuang; Cathy D Poliak; James J Xia
Journal:  J Oral Maxillofac Surg       Date:  2020-12-29       Impact factor: 1.895

8.  Unilateral condylar hyperplasia: a 3-dimensional quantification of asymmetry.

Authors:  Tim J Verhoeven; Jitske W Nolte; Thomas J J Maal; Stefaan J Bergé; Alfred G Becking
Journal:  PLoS One       Date:  2013-03-27       Impact factor: 3.240

9.  Clinical value of 99Tcm-MDP SPECT bone scintigraphy in the diagnosis of unilateral condylar hyperplasia.

Authors:  Bing Wen; Ying Shen; Chang-Yin Wang
Journal:  ScientificWorldJournal       Date:  2014-05-11

10.  Condylectomy and "surgery first" approach: An expedited treatment for condylar hyperplasia in a patient with facial asymmetry.

Authors:  Diego Fernando López; Juan Fernando Aristizábal; Rosana Martínez-Smit
Journal:  Dental Press J Orthod       Date:  2017 Jul-Aug
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