| Literature DB >> 20828139 |
Bertram Barnickel1, Rainer Schobert.
Abstract
The synthesis of macrocyclic 3-acyltetramic acids which are immediate precursors of the fungal herbicide macrocidin A (1) is reported. The crucial closure of the macrocycle was achieved in excellent yield by an unprecedented Williamson etherification of an ω-bromo phenolate generated in situ by a Pd-mediated O-deallylation.Entities:
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Year: 2010 PMID： 20828139 DOI： 10.1021/jo101416x
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354