Literature DB >> 20827800

Molecular engineering: Unnatural design.

Allison Doerr.   

Abstract

Researchers designed an enzyme to carry out the Diels-Alder reaction, an activity not found in nature.

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Year:  2010        PMID： 20827800     DOI： 10.1038/nmeth0910-671

Source DB:  PubMed          Journal:  Nat Methods        ISSN： 1548-7091            Impact factor:   28.547


  1 in total

1.  Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction.

Authors:  Justin B Siegel; Alexandre Zanghellini; Helena M Lovick; Gert Kiss; Abigail R Lambert; Jennifer L St Clair; Jasmine L Gallaher; Donald Hilvert; Michael H Gelb; Barry L Stoddard; Kendall N Houk; Forrest E Michael; David Baker
Journal:  Science       Date:  2010-07-16       Impact factor: 47.728
  1 in total

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