| Literature DB >> 20827590 |
Abstract
Chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq) is a new technology to map protein-DNA interactions in a genome. The genome-wide transcription factor binding site and chromatin modification data produced by ChIP-seq provide invaluable information for studying gene regulation. This chapter reviews basic characteristics of ChIP-seq data and introduces a computational procedure to identify protein-DNA interactions from ChIP-seq experiments.Mesh：
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Year: 2010 PMID： 20827590 DOI： 10.1007/978-1-60761-854-6_9
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745