UNLABELLED: Hepatic parenchymal bleeding (HPB) is a major problem following both trauma and elective hepatic procedures. The present study investigated the effect of the Ankaferd Blood Stopper® (ABS) on HPB. METHOD(S): A total of 20 rats were used. After creating a laceration model in the left lateral hepatic lobe, the area was compressed for 3 minutes with the ABS in the rats in group 1 (n=10) and with 0.9% NaCl-soaked gauze in the rats in group 2 (n=10). RESULTS: The mean change in haematocrit levels between baseline and the 24 hour values in group 1 was lower than group 2 (p=0.045). The mean perioperative bleeding in group 1 was lower than group 2 (p=0.003). The histopa-thologic evaluation revealed that there were no differences between the groups with respect to areas of necrosis (p=0.107) or inflammation (p=0.135). CONCLUSION: Although the ABS does not stop HPB completely, it ensures a statistically significant reduction in HPB.
UNLABELLED: Hepatic parenchymal bleeding (HPB) is a major problem following both trauma and elective hepatic procedures. The present study investigated the effect of the Ankaferd Blood Stopper® (ABS) on HPB. METHOD(S): A total of 20 rats were used. After creating a laceration model in the left lateral hepatic lobe, the area was compressed for 3 minutes with the ABS in the rats in group 1 (n=10) and with 0.9% NaCl-soaked gauze in the rats in group 2 (n=10). RESULTS: The mean change in haematocrit levels between baseline and the 24 hour values in group 1 was lower than group 2 (p=0.045). The mean perioperative bleeding in group 1 was lower than group 2 (p=0.003). The histopa-thologic evaluation revealed that there were no differences between the groups with respect to areas of necrosis (p=0.107) or inflammation (p=0.135). CONCLUSION: Although the ABS does not stop HPB completely, it ensures a statistically significant reduction in HPB.
Authors: K Tabuse; M Katsumi; Y Kobayashi; H Noguchi; H Egawa; O Aoyama; H Kim; Y Nagai; H Yamaue; K Mori Journal: World J Surg Date: 1985-02 Impact factor: 3.352
Authors: Mehmet Kelles; M Tayyar Kalcioglu; Emine Samdanci; Erol Selimoglu; Mustafa Iraz; Murat Cem Miman; Ibrahim C Haznedaroglu Journal: Curr Ther Res Clin Exp Date: 2011-10