Literature DB >> 20825256

Treatment of hypertrophic scars and keloids with a fractional CO2 laser: a personal experience.

Luca Scrimali1, Giuseppe Lomeo, Corrado Nolfo, Gianluca Pompili, Serena Tamburino, Alexei Catalani, Paolo Siragò, Rosario Emanuele Perrotta.   

Abstract

Keloids and hypertrophic scars are both abnormal wound responses in predisposed individuals but they differ in that keloids extend beyond the original wound and almost never regress, while hypertrophic scars remain within the original wound and tend to regress. How keloids grow is not totally clear because there is no animal model; in fact, keloids affect only humans. Different injuries can result in keloids, including burns, surgery, ear piercing, lacerations, abrasions, tattooing, vaccinations, injections, insect bites and any process causing skin inflammation (chicken pox, acne, folliculitis, zoster). Skin or wound tension is considered a critical factor in the formation of keloids and hypertrophic scars. This study is based on eight consecutive patients (four females and four males, F:M = 1:1) with a total of 12 keloids. All of whom were treated monthly with a MiXto SX CO(2) laser, using 13 W of power, 8 SX of index and 40% coverage (density) in combination with Same Plast Gel(®) twice a day. Each scar required 12 treatments, and all the patients, followed up for 1 year after the last treatment, had optimum results and no recurrence.

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Mesh:

Year:  2010        PMID: 20825256     DOI: 10.3109/14764172.2010.514924

Source DB:  PubMed          Journal:  J Cosmet Laser Ther        ISSN: 1476-4172            Impact factor:   2.247


  7 in total

Review 1.  Treatment of keloid scars using light-, laser- and energy-based devices: a contemporary review of the literature.

Authors:  E Forbat; F R Ali; F Al-Niaimi
Journal:  Lasers Med Sci       Date:  2017-10-18       Impact factor: 3.161

2.  Role of hTERT rs2736100 in pathological scarring.

Authors:  Roxana Flavia Ilieș; Salomea-Ruth Halmagyi; Andreea Cătană; Casian Simon Aioanei; Istvan Lukacs; Reka-Eniko Tokes; Ioana Cristina Rotar; Ioan Victor Pop
Journal:  Exp Ther Med       Date:  2022-02-04       Impact factor: 2.447

3.  Comparison of Fractional CO2 Laser, Verapamil, and Triamcinolone for the Treatment of Keloid.

Authors:  Sunil Srivastava; Hiranmayi Kumari; Abhimanyu Singh
Journal:  Adv Wound Care (New Rochelle)       Date:  2019-01-05       Impact factor: 4.730

4.  Clinical and histologic effects from CO2 laser treatment of keloids.

Authors:  Gianfranco Nicoletti; Francesco De Francesco; Carmine Michele Mele; Chiara Cataldo; Roberto Grella; Sergio Brongo; Marina Accardo; Giuseppe Andrea Ferraro; Francesco D'Andrea
Journal:  Lasers Med Sci       Date:  2012-08-21       Impact factor: 3.161

Review 5.  Laser and light-based treatment of Keloids--a review.

Authors:  A D Mamalis; H Lev-Tov; D-H Nguyen; J R Jagdeo
Journal:  J Eur Acad Dermatol Venereol       Date:  2013-08-27       Impact factor: 6.166

6.  Efficacy and safety of laser combination therapy and laser alone therapy for keloid: a systematic review and meta-analysis.

Authors:  Jiahui Chen; Aiyue Chen; Jianhao Zhang; Feipeng Wang; Qiongfang Fang; Ziwei He; Xi Chen; Wancheng Ma; Fulan Hu
Journal:  Lasers Med Sci       Date:  2021-07-20       Impact factor: 3.161

7.  Continuous Wave Fractional CO2 Laser for the Treatment of Upper Eyelid Dermatochalasis and Periorbital Rejuvenation.

Authors:  Melissa Morrison Toyos
Journal:  Photomed Laser Surg       Date:  2017-01-12       Impact factor: 2.796

  7 in total

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