Literature DB >> 2082145

The bex locus in encapsulated Haemophilus influenzae: a chromosomal region involved in capsule polysaccharide export.

J S Kroll1, B Loynds, L N Brophy, E R Moxon.   

Abstract

The nucleotide sequence of a 5.1 kb region in the Haemophilus influenzae type b capsulation locus has been determined and found to contain four open reading frames: bexD, bexC, bexB, and bexA. Comparison of the deduced products of bexC, bexB, and bexA to known proteins, and TnphoA mutagenesis, suggests that they form components of an ATP-driven polysaccharide export apparatus. Furthermore, close sequence similarity between BexA and BexB and products of the kpsT and kpsM genes at the Escherichia coli K5 capsulation locus (Smith et al., 1990--accompanying paper) suggests that capsulation genes in these organisms may have a common ancestry.

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Year:  1990        PMID: 2082145     DOI: 10.1111/j.1365-2958.1990.tb02034.x

Source DB:  PubMed          Journal:  Mol Microbiol        ISSN: 0950-382X            Impact factor:   3.501


  67 in total

1.  Genetic organization of the Escherichia coli K10 capsule gene cluster: identification and characterization of two conserved regions in group III capsule gene clusters encoding polysaccharide transport functions.

Authors:  B R Clarke; R Pearce; I S Roberts
Journal:  J Bacteriol       Date:  1999-04       Impact factor: 3.490

Review 2.  Phase and antigenic variation in bacteria.

Authors:  Marjan W van der Woude; Andreas J Bäumler
Journal:  Clin Microbiol Rev       Date:  2004-07       Impact factor: 26.132

Review 3.  The role of ATP-binding cassette transporters in bacterial pathogenicity.

Authors:  Victoria G Lewis; Miranda P Ween; Christopher A McDevitt
Journal:  Protoplasma       Date:  2012-01-13       Impact factor: 3.356

4.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1991-04-25       Impact factor: 16.971

5.  Transcriptional organization and regulation of expression of region 1 of the Escherichia coli K5 capsule gene cluster.

Authors:  D A Simpson; T C Hammarton; I S Roberts
Journal:  J Bacteriol       Date:  1996-11       Impact factor: 3.490

6.  The Haemophilus influenzae Type b hcsA and hcsB gene products facilitate transport of capsular polysaccharide across the outer membrane and are essential for virulence.

Authors:  Soila Sukupolvi-Petty; Susan Grass; Joseph W St Geme
Journal:  J Bacteriol       Date:  2006-06       Impact factor: 3.490

Review 7.  Haemophilus influenzae type a infection and its prevention.

Authors:  Zhigang Jin; Sandra Romero-Steiner; George M Carlone; John B Robbins; Rachel Schneerson
Journal:  Infect Immun       Date:  2007-03-12       Impact factor: 3.441

8.  Real-time PCR for determining capsular serotypes of Haemophilus influenzae.

Authors:  Younes Maaroufi; Jean-Marc De Bruyne; Corine Heymans; Françoise Crokaert
Journal:  J Clin Microbiol       Date:  2007-05-16       Impact factor: 5.948

9.  Identification of two genes, kpsM and kpsT, in region 3 of the polysialic acid gene cluster of Escherichia coli K1.

Authors:  M S Pavelka; L F Wright; R P Silver
Journal:  J Bacteriol       Date:  1991-08       Impact factor: 3.490

10.  An Aeromonas salmonicida gene which influences a-protein expression in Escherichia coli encodes a protein containing an ATP-binding cassette and maps beside the surface array protein gene.

Authors:  S Chu; T J Trust
Journal:  J Bacteriol       Date:  1993-05       Impact factor: 3.490

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