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Literature DB >> 20821079

Update on the mechanisms of gastric acid secretion.

Abstract

Acid-related disorders represent a major healthcare concern. In recent years, our understanding of the physiologic processes underlying gastric acid secretion has improved notably. The identity of several apical ion transport proteins, which are necessary for acid secretion to take place, has been resolved. The recent developments have uncovered potential therapeutic targets for the treatment of acid-related disorders. This brief review provides an update on the mechanisms of gastric acid secretion, with a particular focus on apical ion transport.

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Year: 2010 PMID： 20821079 DOI： 10.1007/s11894-010-0137-9

Source DB: PubMed Journal: Curr Gastroenterol Rep ISSN： 1522-8037

66 in total

Review 1. Cell biology of acid secretion by the parietal cell.

Authors: Xuebiao Yao; John G Forte
Journal: Annu Rev Physiol Date: 2002-08-05 Impact factor: 19.318

2. Localization, trafficking, and significance for acid secretion of parietal cell Kir4.1 and KCNQ1 K+ channels.

Authors: Marc-André Kaufhold; Anja Krabbenhöft; Penghong Song; Regina Engelhardt; Brigitte Riederer; Michael Fährmann; Nikolaj Klöcker; Winfried Beil; Michael Manns; Susan J Hagen; Ursula Seidler
Journal: Gastroenterology Date: 2008-01-18 Impact factor: 22.682

3. Expression of an extracellular calcium-sensing receptor in rat stomach.

Authors: I Cheng; I Qureshi; N Chattopadhyay; A Qureshi; R R Butters; A E Hall; R R Cima; K V Rogers; S C Hebert; J P Geibel; E M Brown; D I Soybel
Journal: Gastroenterology Date: 1999-01 Impact factor: 22.682

4. Phospho-regulated ACAP4-Ezrin interaction is essential for histamine-stimulated parietal cell secretion.

Authors: Xia Ding; Hui Deng; Dongmei Wang; Jiajia Zhou; Yuejia Huang; Xuannv Zhao; Xue Yu; Ming Wang; Fengsong Wang; Tarsha Ward; Felix Aikhionbare; Xuebiao Yao
Journal: J Biol Chem Date: 2010-04-01 Impact factor: 5.157

5. Forskolin-induced apical membrane insertion of virally expressed, epitope-tagged CFTR in polarized MDCK cells.

Authors: M Howard; X Jiang; D B Stolz; W G Hill; J A Johnson; S C Watkins; R A Frizzell; C M Bruton; P D Robbins; O A Weisz
Journal: Am J Physiol Cell Physiol Date: 2000-08 Impact factor: 4.249

6. Human gastric (H+ + K+)-ATPase gene. Similarity to (Na+ + K+)-ATPase genes in exon/intron organization but difference in control region.

Authors: M Maeda; K Oshiman; S Tamura; M Futai
Journal: J Biol Chem Date: 1990-06-05 Impact factor: 5.157

7. A randomized, comparative study of three doses of AZD0865 and esomeprazole for healing of reflux esophagitis.

Authors: Peter J Kahrilas; John Dent; Karsten Lauritsen; Peter Malfertheiner; Hans Denison; Stefan Franzén; Goran Hasselgren
Journal: Clin Gastroenterol Hepatol Date: 2007-10-22 Impact factor: 11.382

8. Plasma membrane delivery of the gastric H,K-ATPase: the role of beta-subunit glycosylation.

Authors: O Vagin; S Denevich; G Sachs
Journal: Am J Physiol Cell Physiol Date: 2003-05-28 Impact factor: 4.249

9. Three-dimensional reconstruction of cytoplasmic membrane networks in parietal cells.

Authors: Joseph G Duman; Nimesh J Pathak; Mark S Ladinsky; Kent L McDonald; John G Forte
Journal: J Cell Sci Date: 2002-03-15 Impact factor: 5.285

10. Achlorhydria by ezrin knockdown: defects in the formation/expansion of apical canaliculi in gastric parietal cells.

Authors: Atsushi Tamura; Shojiro Kikuchi; Masaki Hata; Tatsuya Katsuno; Takeshi Matsui; Hisayoshi Hayashi; Yuichi Suzuki; Tetsuo Noda; Shoichiro Tsukita; Sachiko Tsukita
Journal: J Cell Biol Date: 2005-04-04 Impact factor: 10.539

9 in total

Review 1. Histamine H₄ receptors in the gastrointestinal tract.

Authors: A Deiteren; J G De Man; P A Pelckmans; B Y De Winter
Journal: Br J Pharmacol Date: 2015-01-12 Impact factor: 8.739

Review 2. KCNE2 and the K (+) channel: the tail wagging the dog.

Authors: Geoffrey W Abbott
Journal: Channels (Austin) Date: 2012-01-01 Impact factor: 2.581

3. Gastro-Protective Effect of Fermented Soybean (Glycine max (L.) Merr.) in a Rat Model of Ethanol/HCl-Induced Gastric Injury.

Authors: Minhee Lee; Dakyung Kim; Hyunji Kim; Sukyung Jo; Ok-Kyung Kim; Jeongmin Lee
Journal: Nutrients Date: 2022-05-16 Impact factor: 6.706

4. Myosin IIB and F-actin control apical vacuolar morphology and histamine-induced trafficking of H-K-ATPase-containing tubulovesicles in gastric parietal cells.

Authors: Paramasivam Natarajan; James M Crothers; Jared E Rosen; Stephanie L Nakada; Milap Rakholia; Curtis T Okamoto; John G Forte; Terry E Machen
Journal: Am J Physiol Gastrointest Liver Physiol Date: 2014-02-27 Impact factor: 4.052