OBJECTIVE: To describe the outcomes of 130 intestinal atresias between 1982 and 2007. METHODS: Records were analyzed for location, demographics, prenatal diagnosis, birth weight, associated anomalies, surgery, establishment of oral intake, re-interventions and mortality. Statistical analyses were performed using Fisher test and ANOVA. RESULTS: There were 59 duodenal (30 male), 63 jejuno-ileal (34 male) and 8 colonic atresias (3 male). Prenatal diagnosis was established in 27 (46%) duodenal (DA), 26 (41%) jejuno-ileal (JIA) and 1 (12.5%) colonic atresias (CA). The mean birth weights, 2,380.5 g (SD 988) DA, 2,814 g (SD 755) JIA and 3,153 g (SD 527) CA were significantly different (p = 0.011). The mean gestational ages were 36, 37 and 37 weeks in DA, JIA and CA, respectively (p-NS). Associated congenital anomalies were seen in 41 (76%) DA, 32 (52%) JIA and 3 (38%) CA (p = 0.08, NS). The median time to full oral feeds after surgery was 18 days in DA, 20 days in JIA and 15.6 days in CA, respectively (p > 0.05). Eight patients with DA and nine patients with JIA underwent repeat surgery for adhesive obstruction. Adhesive bowel obstruction was most common in the first year after surgery in both groups (15/17). Gastroschisis was seen in six (10%) of JIA and three (35%) of CA. Two patients in the JIA group underwent bowel lengthening. Patients with gastroschisis and those with associated anomalies needed prolonged duration of TPN after JIA correction. There was no mortality in the duodenal atresia and colonic atresia groups. Six patients in the JIA group died, three of severe atresias coupled with multiple anomalies and three of cholestasis and sepsis. CONCLUSION: Distal atresias are difficult to diagnose antenatally. Proximal atresias have a significantly lower birth weight than distal atresias. Associated anomaly screening is important in all atresias.
OBJECTIVE: To describe the outcomes of 130 intestinal atresias between 1982 and 2007. METHODS: Records were analyzed for location, demographics, prenatal diagnosis, birth weight, associated anomalies, surgery, establishment of oral intake, re-interventions and mortality. Statistical analyses were performed using Fisher test and ANOVA. RESULTS: There were 59 duodenal (30 male), 63 jejuno-ileal (34 male) and 8 colonic atresias (3 male). Prenatal diagnosis was established in 27 (46%) duodenal (DA), 26 (41%) jejuno-ileal (JIA) and 1 (12.5%) colonic atresias (CA). The mean birth weights, 2,380.5 g (SD 988) DA, 2,814 g (SD 755) JIA and 3,153 g (SD 527) CA were significantly different (p = 0.011). The mean gestational ages were 36, 37 and 37 weeks in DA, JIA and CA, respectively (p-NS). Associated congenital anomalies were seen in 41 (76%) DA, 32 (52%) JIA and 3 (38%) CA (p = 0.08, NS). The median time to full oral feeds after surgery was 18 days in DA, 20 days in JIA and 15.6 days in CA, respectively (p > 0.05). Eight patients with DA and nine patients with JIA underwent repeat surgery for adhesive obstruction. Adhesive bowel obstruction was most common in the first year after surgery in both groups (15/17). Gastroschisis was seen in six (10%) of JIA and three (35%) of CA. Two patients in the JIA group underwent bowel lengthening. Patients with gastroschisis and those with associated anomalies needed prolonged duration of TPN after JIA correction. There was no mortality in the duodenal atresia and colonic atresia groups. Six patients in the JIA group died, three of severe atresias coupled with multiple anomalies and three of cholestasis and sepsis. CONCLUSION: Distal atresias are difficult to diagnose antenatally. Proximal atresias have a significantly lower birth weight than distal atresias. Associated anomaly screening is important in all atresias.
Authors: Karen Walker; Nadia Badawi; Celine H Hamid; Amish Vora; Robert Halliday; Claire Taylor; Edward Shi; G T Roy; Edward Simpson; Andrew J A Holland Journal: J Pediatr Surg Date: 2008-03 Impact factor: 2.545
Authors: Soyhan Bagci; Erwin Brosens; Dick Tibboel; Annelies De Klein; Hanneke Ijsselstijn; Charlotte H W Wijers; Nel Roeleveld; Ivo de Blaauw; Paul M Broens; Iris A L M van Rooij; Alice Hölscher; Thomas M Boemers; Marcus Pauly; Oliver J Münsterer; Eberhard Schmiedeke; Mattias Schäfer; Benno E Ure; Martin Lacher; Vera Choinitzki; Johannes Schumacher; Nadine Zwink; Ekkehart Jenetzky; David Katzer; Joerg Arand; Peter Bartmann; Heiko M Reutter Journal: Eur J Pediatr Date: 2016-03-16 Impact factor: 3.183
Authors: Kin Wai Edwin Chan; Kim Hung Lee; Hei Yi Vicky Wong; Siu Yan Bess Tsui; Yuen Shan Wong; Kit Yi Kristine Pang; Jennifer Wai Cheung Mou; Yuk Him Tam Journal: World J Clin Pediatr Date: 2017-02-08