Literature DB >> 20820525

Alzheimer's disease amyloid beta converting left-handed Z-DNA back to right-handed B-form.

Jie Geng1, Chuanqi Zhao, Jinsong Ren, Xiaogang Qu.   

Abstract

Herein we report that Aβ aggregates, not Aβ monomer, can convert Z-DNA back to B-form, and curcumin, a well-known Aβ aggregation inhibitor, can stop DNA Z-B transition studied by means of biophysical and biochemical methods.

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Year:  2010        PMID： 20820525     DOI： 10.1039/c0cc02049d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

1.  Construction of ssDNA-Attached LR-Chimera Involving Z-DNA for ZBP1 Binding Analysis.

Authors:  Lin Li; Ran An; Xingguo Liang
Journal:  Molecules       Date:  2022-06-09       Impact factor: 4.927

2.  Contrasting enantioselective DNA preference: chiral helical macrocyclic lanthanide complex binding to DNA.

Authors:  Chuanqi Zhao; Jinsong Ren; Janusz Gregoliński; Jerzy Lisowski; Xiaogang Qu
Journal:  Nucleic Acids Res       Date:  2012-06-06       Impact factor: 16.971

3.  Lanthanum induced B-to-Z transition in self-assembled Y-shaped branched DNA structure.

Authors:  Ashok K Nayak; Aseem Mishra; Bhabani S Jena; Barada K Mishra; Umakanta Subudhi
Journal:  Sci Rep       Date:  2016-05-31       Impact factor: 4.379

4.  Nonalternating purine pyrimidine sequences can form stable left-handed DNA duplex by strong topological constraint.

Authors:  Lin Li; Yaping Zhang; Wanzhi Ma; Hui Chen; Mengqin Liu; Ran An; Bingxiao Cheng; Xingguo Liang
Journal:  Nucleic Acids Res       Date:  2022-01-25       Impact factor: 16.971

5.  Praseodymium promotes B-Z transition in self-assembled DNA nanostructures.

Authors:  Madhabi M Bhanjadeo; Umakanta Subudhi
Journal:  RSC Adv       Date:  2019-02-06       Impact factor: 4.036

Review 6.  Curcumin Scaffold as a Multifunctional Tool for Alzheimer's Disease Research.

Authors:  Haijun Yang; Fantian Zeng; Yunchun Luo; Chao Zheng; Chongzhao Ran; Jian Yang
Journal:  Molecules       Date:  2022-06-17       Impact factor: 4.927

Review 7.  The toxicity of amyloid β oligomers.

Authors:  Li Na Zhao; Hon Wai Long; Yuguang Mu; Lock Yue Chew
Journal:  Int J Mol Sci       Date:  2012-06-13       Impact factor: 6.208

8.  Lighting up left-handed Z-DNA: photoluminescent carbon dots induce DNA B to Z transition and perform DNA logic operations.

Authors:  Lingyan Feng; Andong Zhao; Jinsong Ren; Xiaogang Qu
Journal:  Nucleic Acids Res       Date:  2013-06-27       Impact factor: 16.971

9.  Prion Protein PRNP: A New Player in Innate Immunity? The Aβ Connection.

Authors:  Richard Lathe; Jean-Luc Darlix
Journal:  J Alzheimers Dis Rep       Date:  2017-12-16
  9 in total

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