Literature DB >> 20819330

Healthcare associated infection: novel strategies and antimicrobial implants to prevent surgical site infection.

David Leaper1, Andrew J McBain, Axel Kramer, Ojan Assadian, Jose Luis Alfonso Sanchez, Jukka Lumio, Martin Kiernan.   

Abstract

This report is based on a Hygienist Panel Meeting held at St Anne's Manor, Wokingham on 24-25 June 2009. The panel agreed that greater use should be made of antiseptics to reduce reliance on antibiotics with their associated risk of antibiotic resistance. When choosing an antiseptic for clinical use, the Biocompatibility Index, which considers both the microbiocidal activity and any cytotoxic effects of an antiseptic agent, was considered to be a useful tool. The need for longer and more proactive post-discharge surveillance of surgical patients was also agreed to be a priority, especially given the current growth of day-case surgery. The introduction of surgical safety checklists, such as the World Health Organization's Safe Surgery Saves Lives initiative, is a useful contribution to improving safety and prevention of SSIs and should be used universally. Considering sutures as 'implants', with a hard or non-shedding surface to which micro-organisms can form biofilm and cause surgical site infections, was felt to be a useful concept.

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Year:  2010        PMID: 20819330      PMCID: PMC3182781          DOI: 10.1308/003588410X12699663905276

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  46 in total

1.  Bacterial adherence to surgical sutures: can antibacterial-coated sutures reduce the risk of microbial contamination?

Authors:  Charles E Edmiston; Gary R Seabrook; Michael P Goheen; Candace J Krepel; Christopher P Johnson; Brian D Lewis; Kellie R Brown; Jonathan B Towne
Journal:  J Am Coll Surg       Date:  2006-08-22       Impact factor: 6.113

2.  Antimicrobial suture wound closure for cerebrospinal fluid shunt surgery: a prospective, double-blinded, randomized controlled trial.

Authors:  Curtis J Rozzelle; Jody Leonardo; Veetai Li
Journal:  J Neurosurg Pediatr       Date:  2008-08       Impact factor: 2.375

3.  In vivo antibacterial efficacy of MONOCRYL plus antibacterial suture (Poliglecaprone 25 with triclosan).

Authors:  Xintian Ming; Michele Nichols; Stephen Rothenburger
Journal:  Surg Infect (Larchmt)       Date:  2007-04       Impact factor: 2.150

4.  Feasibility and clinical applicability of polihexanide for treatment of second-degree burn wounds.

Authors:  G Daeschlein; O Assadian; J C Bruck; C Meinl; A Kramer; S Koch
Journal:  Skin Pharmacol Physiol       Date:  2007-08-23       Impact factor: 3.479

5.  In vivo and in vitro antibacterial efficacy of PDS plus (polidioxanone with triclosan) suture.

Authors:  Xintian Ming; Stephen Rothenburger; Michele M Nichols
Journal:  Surg Infect (Larchmt)       Date:  2008-08       Impact factor: 2.150

6.  Effect of Octenisept antiseptic on bioburden of neoplastic ulcers in patients with advanced cancer.

Authors:  M Sopata; M Ciupińska; A Głowacka; Z Muszyński; E Tomaszewska
Journal:  J Wound Care       Date:  2008-01       Impact factor: 2.072

7.  Biocompatibility index of antiseptic agents by parallel assessment of antimicrobial activity and cellular cytotoxicity.

Authors:  Gerald Müller; Axel Kramer
Journal:  J Antimicrob Chemother       Date:  2008-03-25       Impact factor: 5.790

8.  Suture-related keratitis caused by Corynebacterium macginleyi.

Authors:  Takashi Suzuki; Hirotoshi Iihara; Toshihiko Uno; Yuko Hara; Kiyofumi Ohkusu; Hiroyuki Hata; Masachika Shudo; Yuichi Ohashi
Journal:  J Clin Microbiol       Date:  2007-10-03       Impact factor: 5.948

9.  Are we really seeing the total costs of surgical site infections? A Spanish study.

Authors:  Jose Luis Alfonso; Sergio Blasco Pereperez; Jose Moreno Canoves; Mercedes Melgar Martinez; Isabel Martinez Martinez; Jose M Martin-Moreno
Journal:  Wound Repair Regen       Date:  2007 Jul-Aug       Impact factor: 3.617

10.  Study of the efficacy of coated Vicryl plus antibacterial suture in an animal model of orthopedic surgery.

Authors:  Fernando Marco; Raquel Vallez; Pablo Gonzalez; Luis Ortega; Jose de la Lama; Luis Lopez-Duran
Journal:  Surg Infect (Larchmt)       Date:  2007-06       Impact factor: 2.150

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  15 in total

1.  Topical antiseptics in wound care: time for reflection.

Authors:  David Leaper
Journal:  Int Wound J       Date:  2011-12       Impact factor: 3.315

Review 2.  [Definition and management of wound infections].

Authors:  S Maier; P Körner; S Diedrich; A Kramer; C-D Heidecke
Journal:  Chirurg       Date:  2011-03       Impact factor: 0.955

Review 3.  The role of antimicrobial sutures in preventing surgical site infection.

Authors:  D Leaper; P Wilson; O Assadian; C Edmiston; M Kiernan; A Miller; G Bond-Smith; J Yap
Journal:  Ann R Coll Surg Engl       Date:  2017-07       Impact factor: 1.891

Review 4.  Controlled release drug delivery systems to improve post-operative pharmacotherapy.

Authors:  Prabhat Bhusal; Jeff Harrison; Manisha Sharma; David S Jones; Andrew G Hill; Darren Svirskis
Journal:  Drug Deliv Transl Res       Date:  2016-10       Impact factor: 4.617

5.  Use of affinity allows anti-inflammatory and anti-microbial dual release that matches suture wound resolution.

Authors:  Rebecca M Haley; Victoria R Qian; Greg D Learn; Horst A von Recum
Journal:  J Biomed Mater Res A       Date:  2019-03-20       Impact factor: 4.396

6.  Multimodal imaging guides surgical management in a preclinical spinal implant infection model.

Authors:  Stephen D Zoller; Howard Y Park; Tove Olafsen; Charles Zamilpa; Zachary Dc Burke; Gideon Blumstein; William L Sheppard; Christopher D Hamad; Kellyn R Hori; Jen-Chieh Tseng; Julie Czupryna; Craig McMannus; Jason T Lee; Mafalda Bispo; Francisco Romero Pastrana; Elisa Jm Raineri; Jeffery F Miller; Lloyd S Miller; Jan Maarten van Dijl; Kevin P Francis; Nicholas M Bernthal
Journal:  JCI Insight       Date:  2019-02-07

7.  Two Regulators, PA3898 and PA2100, Modulate the Pseudomonas aeruginosa Multidrug Resistance MexAB-OprM and EmrAB Efflux Pumps and Biofilm Formation.

Authors:  Yun Heacock-Kang; Zhenxin Sun; Jan Zarzycki-Siek; Kanchana Poonsuk; Ian A McMillan; Rungtip Chuanchuen; Tung T Hoang
Journal:  Antimicrob Agents Chemother       Date:  2018-11-26       Impact factor: 5.191

8.  Novel dual regulators of Pseudomonas aeruginosa essential for productive biofilms and virulence.

Authors:  Yun Heacock-Kang; Jan Zarzycki-Siek; Zhenxin Sun; Kanchana Poonsuk; Andrew P Bluhm; Darlene Cabanas; Dawson Fogen; Ian A McMillan; Rungtip Chuanchuen; Tung T Hoang
Journal:  Mol Microbiol       Date:  2018-07-31       Impact factor: 3.501

9.  Review of indicators for cross-sectoral optimization of nosocomial infection prophylaxis - a perspective from structurally- and process-oriented hygiene.

Authors:  Nils-Olaf Hübner; Steffen Fleßa; Ralf Jakisch; Ojan Assadian; Axel Kramer
Journal:  GMS Krankenhhyg Interdiszip       Date:  2012-04-04

10.  In vitro evaluation of novel antimicrobial coatings for surgical sutures using octenidine.

Authors:  A Obermeier; J Schneider; P Föhr; S Wehner; K-D Kühn; A Stemberger; M Schieker; R Burgkart
Journal:  BMC Microbiol       Date:  2015-09-24       Impact factor: 3.605

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