Literature DB >> 2081931

Early ductal lesions of pancreatic carcinogenesis in animals and humans.

Y Konishi1, K Mizumoto, S Kitazawa, T Tsujiuchi, M Tsutsumi, T Kamano.   

Abstract

Two cases of human early pancreatic duct adenocarcinoma were presented, and ductal lesions observed histologically were compared to those induced in hamsters using a rapid-production model of pancreatic carcinoma. In human cases, direct histologic evidence was obtained to suggest that cancerous changes arose from duct epithelial cell hyperplasia, because lesions of hyperplasia and carcinoma coexisted in continuity. In hamster serial-killing studies, it was suggested that carcinoma developed through atypical ductal hyperplasia.

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Year:  1990        PMID： 2081931     DOI： 10.1007/BF02924223

Source DB:  PubMed          Journal:  Int J Pancreatol        ISSN： 0169-4197


  6 in total

1.  Pancreatic duct hyperplasia and cancer.

Authors:  S C SOMMERS; S A MURPHY; S WARREN
Journal:  Gastroenterology       Date:  1954-11       Impact factor: 22.682

2.  Rapid production of pancreatic carcinoma by initiation with N-nitroso-bis(2-oxopropyl)amine and repeated augmentation pressure in hamsters.

Authors:  K Mizumoto; M Tsutsumi; A Denda; Y Konishi
Journal:  J Natl Cancer Inst       Date:  1988-12-07       Impact factor: 13.506

3.  Early pancreatic duct adenocarcinoma.

Authors:  K Mizumoto; T Inagaki; M Koizumi; M Uemura; M Ogawa; S Kitazawa; M Tsutsumi; M Toyokawa; Y Konishi
Journal:  Hum Pathol       Date:  1988-02       Impact factor: 3.466

4.  Cancer of the pancreas. 50 years of surgery.

Authors:  B Gudjonsson
Journal:  Cancer       Date:  1987-11-01       Impact factor: 6.860

5.  Collective review of small carcinomas of the pancreas.

Authors:  R Tsuchiya; T Noda; N Harada; T Miyamoto; T Tomioka; K Yamamoto; T Yamaguchi; K Izawa; T Tsunoda; R Yoshino
Journal:  Ann Surg       Date:  1986-01       Impact factor: 12.969

6.  Surgical treatment for carcinoma of the pancreas. Experience in 272 patients.

Authors:  S Matsuno; T Sato
Journal:  Am J Surg       Date:  1986-11       Impact factor: 2.565
  6 in total
  6 in total

1.  Investigational Strategies for Detection and Intervention in Early-Stage Pancreatic Cancer. April 24-27, Annapolis, Maryland. Abstracts.

Authors: 
Journal:  Int J Pancreatol       Date:  1994 Oct-Dec

2.  Structural changes of the exocrine pancreas in a patient with cholecystolithiasis.

Authors:  L Magnani; D Bani; G Biliotti; T Bani Sacchi
Journal:  Int J Pancreatol       Date:  1992-08

3.  Novel immunohistochemical marker, integrin α(V)β(3), for BOP-induced early lesions in hamster pancreatic ductal carcinogenesis.

Authors:  Tsukasa Kitahashi; Mitsuyoshi Yoshimoto; Toshio Imai
Journal:  Oncol Lett       Date:  2011-01-21       Impact factor: 2.967

4.  Murine pancreatic ductal adenocarcinoma produced by in vitro transduction of polyoma middle T oncogene into the islets of Langerhans.

Authors:  T Yoshida; D Hanahan
Journal:  Am J Pathol       Date:  1994-09       Impact factor: 4.307

5.  Promoting Effects of Sucrose-rich Diet on N-Nitrosobis (2-oxopropyl) amine-induced Pancreatic Carcinogenesis in Hamsters.

Authors:  Akika Sakamoto; Michishi Goya; Yoko Degawa; Masayuki Mitsui; Toshio Mori; Kazutoshi Tamura; Masahiro Tsutsumi
Journal:  J Toxicol Pathol       Date:  2010-04-05       Impact factor: 1.628

6.  K-ras gene mutation in early ductal lesions induced in a rapid production model for pancreatic carcinomas in Syrian hamsters.

Authors:  M Tsutsumi; S Kondoh; O Noguchi; K Horiguchi; E Kobayashi; S Okita; K Ohashi; K Honoki; T Tsujiuchi; Y Konishi
Journal:  Jpn J Cancer Res       Date:  1993-11
  6 in total

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