Literature DB >> 2081917

Aneuploid DNA content in pancreatic adenocarcinoma.

T M Wido1, J L Myles, L Pisharodi, T Sawyer, K Kim, A F Gohara, J M Howard.   

Abstract

DNA content measurements were performed by flow cytometry on eight ductal-type pancreatic adenocarcinomas. The majority of the neoplasms contained an aneuploid DNA content, with hyperdiploid DNA content being the most common abnormality. Two neoplasms had a diploid DNA content. These latter two patients are alive at 11 mo and 3 mo. The data suggest that a large percentage of pancreatic adenocarcinomas have an aneuploid DNA content. Further study is needed to evaluate the relationship between aneuploid DNA content and survival.

Entities:  

Mesh:

Substances:

Year:  1990        PMID: 2081917     DOI: 10.1007/BF02924229

Source DB:  PubMed          Journal:  Int J Pancreatol        ISSN: 0169-4197


  10 in total

1.  Cancer statistics, 1989.

Authors:  E Silverberg; J A Lubera
Journal:  CA Cancer J Clin       Date:  1989 Jan-Feb       Impact factor: 508.702

2.  The prognostic significance of the DNA distribution in squamous-cell carcinomas of the uterine cervix.

Authors:  A Göppinger; N Freudenberg; A Ross; H G Hillemans; M Hilgarth
Journal:  Anal Quant Cytol Histol       Date:  1986-06       Impact factor: 0.302

3.  Cellular DNA content as a predictor of response to chemotherapy in infants with unresectable neuroblastoma.

Authors:  A T Look; F A Hayes; R Nitschke; N B McWilliams; A A Green
Journal:  N Engl J Med       Date:  1984-07-26       Impact factor: 91.245

4.  The influence of tumour cell DNA abnormalities on survival in colorectal cancer.

Authors:  N C Armitage; R A Robins; D F Evans; D R Turner; R W Baldwin; J D Hardcastle
Journal:  Br J Surg       Date:  1985-10       Impact factor: 6.939

5.  Flow-cytometric DNA analysis in primary breast carcinomas and clinicopathological correlations.

Authors:  S B Ewers; E Långström; B Baldetorp; D Killander
Journal:  Cytometry       Date:  1984-07

6.  The significance of ploidy and proliferation in the clinical and biological evaluation of bladder tumours: a study of 100 untreated cases.

Authors:  B Tribukait; H Gustafson; P L Esposti
Journal:  Br J Urol       Date:  1982-04

7.  DNA flow cytometry in human bladder carcinoma.

Authors:  S D Fosså; E Thorud; E O Pettersen; M C Shoaib; O Scott-Knudsen; S Ous
Journal:  Pathol Res Pract       Date:  1986-06       Impact factor: 3.250

8.  Flow DNA analysis of primary bone tumors. Relationship between cellular DNA content and histopathologic classification.

Authors:  A Kreicbergs; C Silvferswärd; B Tribukait
Journal:  Cancer       Date:  1984-01-01       Impact factor: 6.860

9.  Prognostic importance of blast cell DNA content in childhood acute lymphoblastic leukemia.

Authors:  A T Look; P K Roberson; D L Williams; G Rivera; W P Bowman; C H Pui; J Ochs; M Abromowitch; D Kalwinsky; G V Dahl
Journal:  Blood       Date:  1985-05       Impact factor: 22.113

10.  Prognostic value of nuclear DNA content in follicular thyroid tumours.

Authors:  M Bäckdahl; G Auer; G Forsslund; P O Granberg; B Hamberger; G Lundell; T Löwhagen; A Zetterberg
Journal:  Acta Chir Scand       Date:  1986-01
  10 in total
  2 in total

1.  Overexpression of HER2/neu oncogene in pancreatic cancer correlates with shortened survival.

Authors:  S Lei; H E Appert; B Nakata; D R Domenico; K Kim; J M Howard
Journal:  Int J Pancreatol       Date:  1995-02

2.  Oncogenic KRAS triggers MAPK-dependent errors in mitosis and MYC-dependent sensitivity to anti-mitotic agents.

Authors:  David Perera; Ashok R Venkitaraman
Journal:  Sci Rep       Date:  2016-07-14       Impact factor: 4.379

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.