Literature DB >> 20818330

Fragile privileges: autoimmunity in brain and eye.

Hartmut Wekerle1, De-ming Sun.   

Abstract

Brain and eye tissues are subject to a reduced version of immune surveillance, which has evolved to protect the particularly sensitive tissues from accidental bystander damage created by regular inflammatory responses. Yet, there are autoimmune diseases in both organs. This review discusses the nature of immune reactivity in the healthy eye and brain tissues, and mechanisms that can overcome the protective barriers to create tissue specific disease.

Entities:  

Mesh：

Year:  2010        PMID： 20818330      PMCID： PMC4002320          DOI： 10.1038/aps.2010.149

Source DB:  PubMed          Journal:  Acta Pharmacol Sin        ISSN： 1671-4083            Impact factor:   6.150


  36 in total

1.  Migratory activity and functional changes of green fluorescent effector cells before and during experimental autoimmune encephalomyelitis.

Authors:  A Flügel; T Berkowicz; T Ritter; M Labeur; D E Jenne; Z Li; J W Ellwart; M Willem; H Lassmann; H Wekerle
Journal:  Immunity       Date:  2001-05       Impact factor: 31.745

2.  CD4+ NKT cells, but not conventional CD4+ T cells, are required to generate efferent CD8+ T regulatory cells following antigen inoculation in an immune-privileged site.

Authors:  Takahiko Nakamura; Koh-Hei Sonoda; Douglas E Faunce; Jenny Gumperz; Takashi Yamamura; Sachiko Miyake; Joan Stein-Streilein
Journal:  J Immunol       Date:  2003-08-01       Impact factor: 5.422

Review 3.  Immunologically privileged sites.

Authors:  C F Barker; R E Billingham
Journal:  Adv Immunol       Date:  1977       Impact factor: 3.543

4.  Immune response to immunization via the anterior chamber of the eye. I. F. lymphocyte-induced immune deviation.

Authors:  H J Kaplan; J W Streilein
Journal:  J Immunol       Date:  1977-03       Impact factor: 5.422

5.  The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis.

Authors:  A Ben-Nun; H Wekerle; I R Cohen
Journal:  Eur J Immunol       Date:  1981-03       Impact factor: 5.532

6.  Immune response to immunization via the anterior chamber of the eye. II. An analysis of F1 lymphocyte-induced immune deviation.

Authors:  H J Kaplan; J W Streilein
Journal:  J Immunol       Date:  1978-03       Impact factor: 5.422

7.  MIP-2 recruits NKT cells to the spleen during tolerance induction.

Authors:  D E Faunce; K H Sonoda; J Stein-Streilein
Journal:  J Immunol       Date:  2001-01-01       Impact factor: 5.422

8.  Experimental autoimmune uveitis in the athymic nude rat.

Authors:  M C Salinas-Carmona; R B Nussenblatt; I Gery
Journal:  Eur J Immunol       Date:  1982-06       Impact factor: 5.532

9.  Drainage of interstitial fluid from different regions of rat brain.

Authors:  I Szentistványi; C S Patlak; R A Ellis; H F Cserr
Journal:  Am J Physiol       Date:  1984-06

10.  Induction of anterior chamber-associated immune deviation requires an intact, functional spleen.

Authors:  J W Streilein; J Y Niederkorn
Journal:  J Exp Med       Date:  1981-05-01       Impact factor: 14.307
View more
  7 in total

1.  Visualizing context-dependent calcium signaling in encephalitogenic T cells in vivo by two-photon microscopy.

Authors:  Nikolaos I Kyratsous; Isabel J Bauer; Guokun Zhang; Marija Pesic; Ingo Bartholomäus; Marsilius Mues; Ping Fang; Miriam Wörner; Stephanie Everts; Joachim W Ellwart; Joanna M Watt; Barry V L Potter; Reinhard Hohlfeld; Hartmut Wekerle; Naoto Kawakami
Journal:  Proc Natl Acad Sci U S A       Date:  2017-07-17       Impact factor: 11.205

2.  Genetic analyses of HIV env associated with uveitis in antiretroviral-naive individuals.

Authors:  Corey A Williams-Wietzikoski; Isaac D So; Marta E Bull; Tanawan Samleerat; Kessara Pathanapitoon; Paradee Kunavisarut; Natedao Kongyai; Nicole Ngo-Giang-Huong; Lisa M Frenkel; Wasna Sirirungsi
Journal:  AIDS       Date:  2017-08-24       Impact factor: 4.177

Review 3.  Revisiting the Mechanisms of CNS Immune Privilege.

Authors:  Antoine Louveau; Tajie H Harris; Jonathan Kipnis
Journal:  Trends Immunol       Date:  2015-10       Impact factor: 16.687

Review 4.  NLRs as Helpline in the Brain: Mechanisms and Therapeutic Implications.

Authors:  Shalini Singh; Sushmita Jha
Journal:  Mol Neurobiol       Date:  2018-03-06       Impact factor: 5.590

5.  Sex Difference in Oxidative Stress Parameters in Spinal Cord of Rats with Experimental Autoimmune Encephalomyelitis: Relation to Neurological Deficit.

Authors:  Mirjana Dimitrijević; Jelena Kotur-Stevuljević; Zorica Stojić-Vukanić; Ivana Vujnović; Ivan Pilipović; Mirjana Nacka-Aleksić; Gordana Leposavić
Journal:  Neurochem Res       Date:  2016-11-03       Impact factor: 3.996

6.  Adoptive transfer of immune cells from glaucomatous mice provokes retinal ganglion cell loss in recipients.

Authors:  Oliver W Gramlich; Qiong J Ding; Wei Zhu; Amy Cook; Michael G Anderson; Markus H Kuehn
Journal:  Acta Neuropathol Commun       Date:  2015-09-15       Impact factor: 7.801

Review 7.  Neuroinflammation-Driven Lymphangiogenesis in CNS Diseases.

Authors:  Martin Hsu; Collin Laaker; Matyas Sandor; Zsuzsanna Fabry
Journal:  Front Cell Neurosci       Date:  2021-06-23       Impact factor: 6.147
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.