Literature DB >> 20815764

Recent advances in hydrogen research as a therapeutic medical gas.

Chien-Sheng Huang1, Tomohiro Kawamura, Yoshiya Toyoda, Atsunori Nakao.   

Abstract

Recent basic and clinical research has revealed that hydrogen is an important physiological regulatory factor with antioxidant, anti-inflammatory and anti-apoptotic protective effects on cells and organs. Therapeutic hydrogen has been applied by different delivery methods including straightforward inhalation, drinking hydrogen dissolved in water and injection with hydrogen-saturated saline. This review summarizes currently available data regarding the protective role of hydrogen, provides an outline of recent advances in research on the use of hydrogen as a therapeutic medical gas in diverse models of disease and discusses the feasibility of hydrogen as a therapeutic strategy. It is not an overstatement to say that hydrogen's impact on therapeutic and preventive medicine could be enormous in the future.

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Year:  2010        PMID： 20815764     DOI： 10.3109/10715762.2010.500328

Source DB:  PubMed          Journal:  Free Radic Res        ISSN： 1029-2470


  95 in total

1.  Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats.

Authors:  Qiang Sun; Tomohiro Kawamura; Kosuke Masutani; Ximei Peng; Qing Sun; Donna B Stolz; John P Pribis; Timothy R Billiar; Xuejun Sun; Christian A Bermudez; Yoshiya Toyoda; Atsunori Nakao
Journal:  Cardiovasc Res       Date:  2012-01-27       Impact factor: 10.787

2.  Inhalation of hydrogen gas attenuates ouabain-induced auditory neuropathy in gerbils.

Authors:  Juan Qu; Yun-na Gan; Ke-liang Xie; Wen-bo Liu; Ya-fei Wang; Ren-yi Hei; Wen-juan Mi; Jian-hua Qiu
Journal:  Acta Pharmacol Sin       Date:  2012-03-05       Impact factor: 6.150

3.  Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy.

Authors:  Qingxi Yang; Guangdong Ji; Rongtao Pan; Yinghui Zhao; Peng Yan
Journal:  Mol Clin Oncol       Date:  2017-09-01

4.  Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells.

Authors:  Guo-Dan Liu; Hong Zhang; Lin Wang; Qing Han; Shi-Feng Zhou; Ping Liu
Journal:  Int J Ophthalmol       Date:  2013-06-18       Impact factor: 1.779

5.  Molecular hydrogen affects body composition, metabolic profiles, and mitochondrial function in middle-aged overweight women.

Authors:  D Korovljev; T Trivic; P Drid; S M Ostojic
Journal:  Ir J Med Sci       Date:  2017-05-30       Impact factor: 1.568

6.  The Effects of Molecular Hydrogen and Suberoylanilide Hydroxamic Acid on Paraquat-Induced Production of Reactive Oxygen Species and TNF-α in Macrophages.

Authors:  Jiaoyang Li; Xizi Wu; Yao Chen; Renqing Zeng; Yangzi Zhao; Panpan Chang; Danna Wang; Qianwen Zhao; Yunlei Deng; Yongqing Li; Hasan B Alam; Wei Chong
Journal:  Inflammation       Date:  2016-12       Impact factor: 4.092

7.  Profiling molecular changes induced by hydrogen treatment of lung allografts prior to procurement.

Authors:  Yugo Tanaka; Norihisa Shigemura; Tomohiro Kawamura; Kentaro Noda; Kumiko Isse; Donna Beer Stolz; Timothy R Billiar; Yoshiya Toyoda; Christian A Bermudez; James Lyons-Weiler; Atsunori Nakao
Journal:  Biochem Biophys Res Commun       Date:  2012-08-07       Impact factor: 3.575

8.  Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.

Authors:  Tomohiro Kawamura; Nobunao Wakabayashi; Norihisa Shigemura; Chien-Sheng Huang; Kosuke Masutani; Yugo Tanaka; Kentaro Noda; Ximei Peng; Toru Takahashi; Timothy R Billiar; Meinoshin Okumura; Yoshiya Toyoda; Thomas W Kensler; Atsunori Nakao
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2013-03-08       Impact factor: 5.464

9.  Lactulose mediates suppression of dextran sodium sulfate-induced colon inflammation by increasing hydrogen production.

Authors:  Xiao Chen; Xiao Zhai; Jiazi Shi; Wen Wu Liu; Hengyi Tao; Xuejun Sun; Zhimin Kang
Journal:  Dig Dis Sci       Date:  2013-01-31       Impact factor: 3.199

10.  Linking hydrogen-mediated boron toxicity tolerance with improvement of root elongation, water status and reactive oxygen species balance: a case study for rice.

Authors:  Yu Wang; Xingliang Duan; Sheng Xu; Ren Wang; Zhaozeng Ouyang; Wenbiao Shen
Journal:  Ann Bot       Date:  2016-09-10       Impact factor: 4.357
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