Literature DB >> 2081494

Effects of the prodrug nabumetone, and its active metabolite, 6-MNA, on human and rat gastric mucosal prostanoids and platelet function.

J Y Jeremy1, D P Mikhailidis, M A Barradas, R M Kirk, P Dandona.   

Abstract

Entities:  

Mesh:

Substances:

Year:  1990        PMID: 2081494     DOI: 10.2165/00003495-199000405-00013

Source DB:  PubMed          Journal:  Drugs        ISSN: 0012-6667            Impact factor:   9.546


× No keyword cloud information.
  12 in total

1.  Prevention of NSAID-induced gastric ulcer with misoprostol: multicentre, double-blind, placebo-controlled trial.

Authors:  D Y Graham; N M Agrawal; S H Roth
Journal:  Lancet       Date:  1988-12-03       Impact factor: 79.321

2.  Comparison of the effects of nabumetone with indomethacin on rat gastric mucosal 6-keto-PGF1 alpha production and on bile salt-induced changes in gastric mucosal function.

Authors:  R Melarange; L C Rashbrook
Journal:  J Pharm Pharmacol       Date:  1987-09       Impact factor: 3.765

Review 3.  Gastric cytoprotection.

Authors:  S J Konturek
Journal:  Scand J Gastroenterol       Date:  1985-06       Impact factor: 2.423

Review 4.  Nonsteroidal anti-inflammatory drug gastropathy. Recognition and response.

Authors:  S H Roth; R E Bennett
Journal:  Arch Intern Med       Date:  1987-12

5.  Cytoprotection of the gastrointestinal mucosa.

Authors:  A Robert
Journal:  Adv Intern Med       Date:  1983

6.  Metabolism of nabumetone (BRL 14777) by various species including man.

Authors:  R E Haddock; D J Jeffery; J A Lloyd; A R Thawley
Journal:  Xenobiotica       Date:  1984-04       Impact factor: 1.908

7.  Non-steroidal anti-inflammatory drugs and life threatening complications of peptic ulceration.

Authors:  C P Armstrong; A L Blower
Journal:  Gut       Date:  1987-05       Impact factor: 23.059

8.  Differential regional changes of prostacyclin and thromboxane A2 synthesis in the intestinal tract of the fasted and semistarved rat.

Authors:  J Y Jeremy; C S Thompson; P Dandona
Journal:  Pflugers Arch       Date:  1987-01       Impact factor: 3.657

9.  Radiochromium (chromium-51) evaluation of gastrointestinal blood loss associated with placebo, aspirin, and nabumetone.

Authors:  A Lussier; E LeBel
Journal:  Am J Med       Date:  1987-10-30       Impact factor: 4.965

10.  Platelet thromboxane A2 synthesizing capacity is enhanced by fasting but diminished by diabetes mellitus in the rat.

Authors:  J Y Jeremy; D P Mikhailidis; C S Thompson; M A Barradas; P Dandona
Journal:  Diabetes Res       Date:  1988-08
View more
  1 in total

1.  Nabumetone. A reappraisal of its pharmacology and therapeutic use in rheumatic diseases.

Authors:  H A Friedel; H D Langtry; M M Buckley
Journal:  Drugs       Date:  1993-01       Impact factor: 9.546

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.