Sir,I read the report by Patted et al. on cardiac Candida krusei infection presenting as a right ventricular mass with great interest.[1] Patted et al. have mentioned that necrotizing enterocolitis and disseminated fungal infection result in an adverse outcome as was seen in their case.[1] Indeed, Candida krusei infection is difficult to treat. Majority of the reported cases with hematogenous spread have died[2] Basic antifungal treatment such as Amphotericin B administration is usually unsuccessful.[3] In the case of cardiac infection, cardiac ischemia leading to death has also been reported.[2] Intravenous Caspofungin therapy has been reported to be the only successful treatment for this condition.[4]
Authors: V Petrocheilou-Paschou; K Georgilis; D Kontoyannis; J Nanas; H Prifti; H Costopoulos; S Stamatelopoulos Journal: Clin Microbiol Infect Date: 2002-12 Impact factor: 8.067