Literature DB >> 20813327

Tamoxifen as first-line treatment in a premenarchal girl with juvenile breast hypertrophy.

Korcan Demir1, Tolga Unuvar, Sanem Eren, Ayhan Abaci, Ece Bober.   

Abstract

BACKGROUND: Juvenile breast hypertrophy is uncommon and is characterized by excessive breast enlargement in the peripubertal period. The clinical entity is thought to result from increased sensitivity of mammary tissue to normal levels of circulating hormones. CASE: Here, we report a female patient, aged 12 years and 6 months, suffering from juvenile breast hypertrophy, who presented at the third month of symptoms and benefited from tamoxifen treatment. COMMENTS: In experienced clinics, use of tamoxifen in the treatment of juvenile breast hypertrophy during the brisk growth period may become a medical alternative to reconstructive surgery. Copyright 2010 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20813327     DOI: 10.1016/j.jpag.2009.11.003

Source DB:  PubMed          Journal:  J Pediatr Adolesc Gynecol        ISSN: 1083-3188            Impact factor:   1.814


  3 in total

1.  Juvenile Breast Hypertrophy: A Successful Breast Reduction of 14.9% Body Weight without Recurrence in a 5-Year Follow-Up.

Authors:  Akmal Hisham; Marzida Abd Latib; Normala Basiron
Journal:  Case Rep Surg       Date:  2017-01-31

2.  Selective Estrogen Receptor Modulators: A Potential Option For Non-Binary Gender-Affirming Hormonal Care?

Authors:  Jane Y Xu; Michele A O'Connell; Lauren Notini; Ada S Cheung; Sav Zwickl; Ken C Pang
Journal:  Front Endocrinol (Lausanne)       Date:  2021-06-18       Impact factor: 5.555

3.  Fatostatin in Combination with Tamoxifen Induces Synergistic Inhibition in ER-Positive Breast Cancer.

Authors:  Ying Liu; Ning Zhang; Hanwen Zhang; Lijuan Wang; Yi Duan; Xiaolong Wang; Tong Chen; Yiran Liang; Yaming Li; Xiaojin Song; Chen Li; Dianwen Han; Bing Chen; Wenjing Zhao; Qifeng Yang
Journal:  Drug Des Devel Ther       Date:  2020-08-26       Impact factor: 4.162

  3 in total

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