Literature DB >> 20813253

Fishing out a sensor for anti-inflammatory oils.

Alan R Saltiel1.   

Abstract

The omega-3 fatty acids have anti-inflammatory and antidiabetic effects in humans. Now, Oh et al. (2010) demonstrate that the G protein-coupled receptor GPR120 is a receptor for omega-3 fatty acids on macrophages and fat cells. Activation of GPR120 by omega-3 fatty acids inhibits multiple inflammation cascades in macrophages and reverses insulin resistance in obese mice. Copyright 2010 Elsevier Inc. All rights reserved.

Entities:  

Year:  2010        PMID： 20813253     DOI： 10.1016/j.cell.2010.08.022

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  8 in total

Review 1.  Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4.

Authors:  G Milligan; E Alvarez-Curto; K R Watterson; T Ulven; B D Hudson
Journal:  Br J Pharmacol       Date:  2015-02-27       Impact factor: 8.739

2.  n-3 Fatty acids block TNF-α-stimulated MCP-1 expression in rat mesangial cells.

Authors:  Montserrat M Diaz Encarnacion; Gina M Warner; Jingfei Cheng; Catherine E Gray; Karl A Nath; Joseph P Grande
Journal:  Am J Physiol Renal Physiol       Date:  2011-03-02

Review 3.  Omega-3 fatty acid supplementation and cardiovascular disease.

Authors:  Donald B Jump; Christopher M Depner; Sasmita Tripathy
Journal:  J Lipid Res       Date:  2012-08-17       Impact factor: 5.922

4.  Unsaturated fatty acids promote the phagocytosis of P. aeruginosa and R. equi by RAW264.7 macrophages.

Authors:  Stephanie Adolph; Herbert Fuhrmann; Julia Schumann
Journal:  Curr Microbiol       Date:  2012-08-18       Impact factor: 2.188

Review 5.  Fatty acid-regulated transcription factors in the liver.

Authors:  Donald B Jump; Sasmita Tripathy; Christopher M Depner
Journal:  Annu Rev Nutr       Date:  2013-03-22       Impact factor: 11.848

6.  Molecular targets of omega 3 and conjugated linoleic Fatty acids - "micromanaging" cellular response.

Authors:  Francesco Visioli; Elena Giordano; Nathalie Marie Nicod; Alberto Dávalos
Journal:  Front Physiol       Date:  2012-02-29       Impact factor: 4.566

Review 7.  The role of the immune system in obesity and insulin resistance.

Authors:  Payal S Patel; Eric D Buras; Ashok Balasubramanyam
Journal:  J Obes       Date:  2013-03-21

8.  Modulation of adipocyte differentiation by omega-3 polyunsaturated fatty acids involves the ubiquitin-proteasome system.

Authors:  Cezary Wójcik; Kimberly Lohe; Chenzhong Kuang; Yan Xiao; Zeida Jouni; Eduard Poels
Journal:  J Cell Mol Med       Date:  2014-04       Impact factor: 5.310
  8 in total

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