Literature DB >> 20812738

Germacrane-type sesquiterpenoids from the roots of Valeriana officinalis var. latifolia.

Peng-Cheng Wang1, Xin-Hui Ran, Rui Chen, Huai-Rong Luo, Yu-Qing Liu, Jun Zhou, You-Xing Zhao.   

Abstract

Eight new germacrane-type sesquiterpenoids, volvalerenals A-E (2-6) and volvalerenic acids A-C (7-9), along with four known compounds, were isolated from a chloroform extract of the roots of Valeriana officinalis var. latifolia. The structures and relative configurations of 2-9 were elucidated on the basis of spectroscopic data interpretation. The effects of all compounds isolated on acetylcholinesterase were evaluated.

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Year:  2010        PMID： 20812738     DOI： 10.1021/np100452a

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  3 in total

Review 1.  The relevance of higher plants in lead compound discovery programs.

Authors:  A Douglas Kinghorn; Li Pan; Joshua N Fletcher; Heebyung Chai
Journal:  J Nat Prod       Date:  2011-06-08       Impact factor: 4.050

Review 2.  Plant Species of Sub-Family Valerianaceae-A Review on Its Effect on the Central Nervous System.

Authors:  Gitishree Das; Han-Seung Shin; Rosa Tundis; Sandra Gonçalves; Ourlad Alzeus G Tantengco; Maria G Campos; Rosaria Acquaviva; Giuseppe Antonio Malfa; Anabela Romano; Joyce Ann H Robles; Mariel Q Clores; Jayanta-Kumar Patra
Journal:  Plants (Basel)       Date:  2021-04-22

3.  Compounds from the roots and rhizomes of Valeriana amurensis protect against neurotoxicity in PC12 cells.

Authors:  Qiuhong Wang; Changfu Wang; Yueming Zuo; Zhibin Wang; Bingyou Yang; Haixue Kuang
Journal:  Molecules       Date:  2012-12-18       Impact factor: 4.411
  3 in total

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