| Literature DB >> 20811358 |
Jeremy D Rotty, Gerald W Hart, Pierre A Coulombe.
Abstract
Mounting evidence suggests that keratin post-translational modifications are crucial for many cellular processes. Now, keratin 18 modified by the addition of an O-linked N-acetylglucosamine residue is shown to be as a critical effector of stress-responsive Akt signalling, providing an important link between keratin glycosylation and cell survival.Entities:
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Year: 2010 PMID: 20811358 DOI: 10.1038/ncb0910-847
Source DB: PubMed Journal: Nat Cell Biol ISSN: 1465-7392 Impact factor: 28.824