Literature DB >> 20810778

Detection of human cytomegalovirus in bronchoalveolar lavage fluid of lung transplant recipients reflects local virus replication and not contamination from the throat.

Heidrun Kerschner1, Peter Jaksch, Barbara Zweytick, Elisabeth Puchhammer-Stöckl.   

Abstract

Whether bronchoalveolar lavage (BAL) fluid may be contaminated with oropharyngeal cytomegalovirus (CMV) has never been investigated. In an analysis of CMV DNA loads in 76 simultaneously obtained BAL fluid and throat wash samples from lung transplant recipients, we show that such contamination is unlikely and that detection of CMV DNA in BAL fluid reflects virus replication in the lung.

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Year:  2010        PMID： 20810778      PMCID： PMC3020805          DOI： 10.1128/JCM.01197-10

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  9 in total

1.  Comparative recovery of cytomegalovirus from saliva, mucolysed induced sputum, and bronchoalveolar lavage fluid from patients at risk for or with acquired immunodeficiency syndrome.

Authors:  J D Rush; V L Ng; P C Hopewell; W K Hadley; J Mills
Journal:  J Clin Microbiol       Date:  1989-12       Impact factor: 5.948

Review 2.  Bronchoalveolar lavage in lung transplantation. State of the art.

Authors:  A H Tiroke; B Bewig; A Haverich
Journal:  Clin Transplant       Date:  1999-04       Impact factor: 2.863

3.  High prevalence of multiple human herpesviruses in saliva from human immunodeficiency virus-infected persons in the era of highly active antiretroviral therapy.

Authors:  Craig S Miller; Joseph R Berger; Yunanan Mootoor; Sergei A Avdiushko; Hua Zhu; Richard J Kryscio
Journal:  J Clin Microbiol       Date:  2006-07       Impact factor: 5.948

4.  Cytomegalovirus shedding in the oral cavity of allogeneic haematopoietic stem cell transplant patients.

Authors:  J de F Correia-Silva; J M N Victória; A L S Guimarães; U E Salomão; M H N G de Abreu; H Bittencourt; R S Gomez
Journal:  Oral Dis       Date:  2007-03       Impact factor: 3.511

5.  Human cytomegalovirus load in plasma and bronchoalveolar lavage fluid: a longitudinal study of lung transplant recipients.

Authors:  Glen P Westall; Alexandra Michaelides; Trevor J Williams; Greg I Snell; Thomas C Kotsimbos
Journal:  J Infect Dis       Date:  2004-08-09       Impact factor: 5.226

Review 6.  Cytomegalovirus and lung transplantation.

Authors:  Martin R Zamora
Journal:  Am J Transplant       Date:  2004-08       Impact factor: 8.086

7.  Bronchiolitis obliterans syndrome and early human cytomegalovirus DNAaemia dynamics after lung transplantation.

Authors:  Glen P Westall; Alexandra Michaelides; Trevor J Williams; Greg I Snell; Thomas C Kotsimbos
Journal:  Transplantation       Date:  2003-06-27       Impact factor: 4.939

Review 8.  Nosocomial pneumonia.

Authors:  Waldemar G Johanson; Lisa L Dever
Journal:  Intensive Care Med       Date:  2002-12-04       Impact factor: 17.440

9.  Shedding of cytomegalovirus and herpesviruses 6, 7, and 8 in saliva of human immunodeficiency virus type 1-infected patients and healthy controls.

Authors:  E Lucht; M Brytting; L Bjerregaard; I Julander; A Linde
Journal:  Clin Infect Dis       Date:  1998-07       Impact factor: 9.079
  9 in total
  2 in total

Review 1.  Clinical utility of viral load in management of cytomegalovirus infection after solid organ transplantation.

Authors:  Raymund R Razonable; Randall T Hayden
Journal:  Clin Microbiol Rev       Date:  2013-10       Impact factor: 26.132

2.  Lower respiratory tract virus findings in mechanically ventilated patients with severe community-acquired pneumonia.

Authors:  J Karhu; T I Ala-Kokko; T Vuorinen; P Ohtonen; H Syrjälä
Journal:  Clin Infect Dis       Date:  2014-04-11       Impact factor: 9.079
  2 in total

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