Literature DB >> 20810128

Vertical wrinkling of the forehead or Procerus sign in Progressive Supranuclear Palsy.

Amit Batla1, Ravi Nehru, Tarun Vijay.   

Abstract

'Procerus sign' has been described as vertical wrinkles in the glabella region and bridge of the nose of patients with Progressive Supranuclear Palsy. The action of Corrugator and Orbicularis Oculi produce the vertical wrinkling. The relevance of this sign in early clinical diagnosis has been established and this sign has gained importance in literature and has been quoted as a useful sign in texts following the original description. We prospectively performed a cross sectional analysis of the facial appearance in subsequent Parkinsonism patients and found statistically significant presence of this sign in PSP compared to other Parkinsonian disorders. We recommend that this should be called "vertical wrinkling of the forehead" to avoid confusion and emphasize the dystonic nature of this condition rather than contraction of a single muscle as indicated by 'Procerus sign'.
Copyright © 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID: 20810128     DOI: 10.1016/j.jns.2010.08.010

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN: 0022-510X            Impact factor:   3.181


  3 in total

Review 1.  Recognizing Atypical Parkinsonisms: "Red Flags" and Therapeutic Approaches.

Authors:  Nikolaus R McFarland; Christopher W Hess
Journal:  Semin Neurol       Date:  2017-05-16       Impact factor: 3.420

Review 2.  Diagnostic Approach to Atypical Parkinsonian Syndromes.

Authors:  Nikolaus R McFarland
Journal:  Continuum (Minneap Minn)       Date:  2016-08

3.  Procerus Sign: Mechanism, Clinical Usefulness, and Controversies.

Authors:  Shakya Bhattacharjee
Journal:  Ann Indian Acad Neurol       Date:  2018 Apr-Jun       Impact factor: 1.383

  3 in total

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