Literature DB >> 20809161

[Nora's lesion. Discussion of a rare bone proliferation].

D Adler1, T Aigner, G von Salis-Soglio, M Gutberlet, C-E Heyde.   

Abstract

Nora's lesion, also known as "bizarre parosteal osteochondromatous proliferation" (BPOP), was first described in 1983 by the pathologist Nora. This lesion is defined as a proliferation of the bone. In most cases the lesion emanates from the intact cortical substance of short bones. It used to be assigned to reactive, heterotopic ossifications. More recent publications described constant genetic alterations supposing a tumorous genesis. Nora lesions are mostly found in the third or fourth decade of life; a preference of sexes is not described in the literature. They are characterized by a typical appearance in radiological diagnostics, but the diagnosis is ultimately determined by histopathological examination. Surgical resection is the therapy of choice.We report the case of a 29-year-old patient with an undetermined proliferation of the proximal ulna. The diagnosis of a Nora's lesion was made. The therapeutic approach, differential diagnosis and corresponding literature are presented and discussed.

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Year:  2010        PMID: 20809161     DOI: 10.1007/s00132-010-1648-7

Source DB:  PubMed          Journal:  Orthopade        ISSN: 0085-4530            Impact factor:   1.087


  17 in total

1.  Bizarre parosteal osteochondromatous proliferation with cortical invasion.

Authors:  T R Helliwell; M A O'Connor; D A Ritchie; L Feldberg; J H Stilwell; M J Jane
Journal:  Skeletal Radiol       Date:  2001-05       Impact factor: 2.199

2.  Bizarre parosteal osteochondromatous proliferation with a t(1;17) translocation.

Authors:  Makoto Endo; Tadashi Hasegawa; Takashi Tashiro; Umio Yamaguchi; Yuki Morimoto; Fumihiko Nakatani; Tadakazu Shimoda
Journal:  Virchows Arch       Date:  2005-05-31       Impact factor: 4.064

3.  Bizarre parosteal osteochondromatous proliferation Nora's lesion of the phalanx.

Authors:  Ramachadaran Muthukrishnan; Venkataraman Sibramanian; Mohammed Fawzy; Arshad Aleem; Umadevi K Ramachandran
Journal:  Saudi Med J       Date:  2006-12       Impact factor: 1.484

Review 4.  Molecular pathology of chondroid neoplasms: part 1, benign lesions.

Authors:  W C Bell; M J Klein; M J Pitt; G P Siegal
Journal:  Skeletal Radiol       Date:  2006-09-23       Impact factor: 2.199

5.  Bizarre parosteal osteochondromatous proliferation of bone (Nora's lesion).

Authors:  M F Meneses; K K Unni; R G Swee
Journal:  Am J Surg Pathol       Date:  1993-07       Impact factor: 6.394

6.  Bizarre parosteal osteochondromatous proliferations of the hands and feet.

Authors:  F E Nora; D C Dahlin; J W Beabout
Journal:  Am J Surg Pathol       Date:  1983-04       Impact factor: 6.394

7.  Florid reactive periostitis and bizarre parosteal osteochondromatous proliferation: pre-biopsy imaging evolution, treatment and outcome.

Authors:  M Sundaram; L Wang; M Rotman; R Howard; A P Saboeiro
Journal:  Skeletal Radiol       Date:  2001-04       Impact factor: 2.199

8.  Cortico-medullary continuity in bizarre parosteal osteochondromatous proliferation mimicking osteochondroma on imaging.

Authors:  Leon D Rybak; Luigia Abramovici; Samuel Kenan; Martin A Posner; Fiona Bonar; German C Steiner
Journal:  Skeletal Radiol       Date:  2007-04-12       Impact factor: 2.199

9.  Distinct chromosomal rearrangements in subungual (Dupuytren) exostosis and bizarre parosteal osteochondromatous proliferation (Nora lesion).

Authors:  Eduardo Zambrano; Vânia Nosé; Antonio R Perez-Atayde; Mark Gebhardt; M Timothy Hresko; Paul Kleinman; Kathleen E Richkind; Harry P W Kozakewich
Journal:  Am J Surg Pathol       Date:  2004-08       Impact factor: 6.394

10.  Bizarre parosteal osteochondromatous proliferation (Nora's lesion): a retrospective study of 12 cases, 2 arising in long bones.

Authors:  Luigia Abramovici; German C Steiner
Journal:  Hum Pathol       Date:  2002-12       Impact factor: 3.466

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  2 in total

1.  [Bizarre parosteal osteochondromatous proliferation of the metatarsal bone].

Authors:  C Hartog; V Centmaier-Molnar; R Patzwahl; D Pfofe; M Wiewiorski
Journal:  Orthopade       Date:  2016-10       Impact factor: 1.087

2.  Differential diagnosis of BPOP arising in relation to patella.

Authors:  Jitendra Nath Pal; Maitreyee Kar; Sunit Hazra; Anindya Basu
Journal:  J Orthop Case Rep       Date:  2015 Oct-Dec
  2 in total

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