Literature DB >> 20808741

Use of botulinum toxin in cheiloplasty: A new method to decrease tension.

Iván Marcelo Cueva Galárraga1.   

Abstract

OBJECTIVE: To determine if the use of botulinum toxin during cheiloplasty could help in the management of tension at the surgical wound level.
INTERVENTIONS: Five children younger than six months of age, who were born with complete cleft lip and palate, were treated with a dose of 10 units of botulinum toxin injected into the upper lip during surgery. Before the surgery, an electromyographic study was carried out on the patients' upper lips. A Millard-type cheiloplasty was performed and 10 days later, a second electromyographic study was performed on the upper lips of all the patients.
RESULTS: There was a significant change (P<0.039) in the electromyographic tracing obtained after the application of botulinum toxin, especially during rest.
CONCLUSION: As confirmed by electromyography, botulinum toxin effectively inhibits the action of the orbicularis oris muscle, especially when at rest; consequently, the tension is decreased at the level of the surgical wound.

Entities:  

Keywords:  Botulinum toxin; Cheiloplasty; Cleft lip

Year:  2009        PMID: 20808741      PMCID: PMC2740606          DOI: 10.1177/229255030901700313

Source DB:  PubMed          Journal:  Can J Plast Surg        ISSN: 1195-2199


  8 in total

1.  Botulinum toxin to improve results in cleft lip repair.

Authors:  Travis T Tollefson; Craig M Senders; Jonathan M Sykes; Paul J Byorth
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Review 2.  Botulinum A exotoxin use in clinical dermatology.

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Journal:  J Am Acad Dermatol       Date:  1996-05       Impact factor: 11.527

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Journal:  Cleft Palate Craniofac J       Date:  1992-01

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Journal:  Plast Reconstr Surg       Date:  1988-11       Impact factor: 4.730

7.  Lip pressure changes following lip repair in infants with unilateral clefts of the lip and palate.

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Journal:  Plast Reconstr Surg       Date:  1984-10       Impact factor: 4.730

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Authors:  G Göz; U Joos; W Schilli
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  8 in total
  5 in total

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Authors:  M S Archana
Journal:  Saudi Dent J       Date:  2015-12-21

Review 2.  New Uses of AbobotulinumtoxinA in Aesthetics.

Authors:  Joel Schlessinger; Erin Gilbert; Joel L Cohen; Joely Kaufman
Journal:  Aesthet Surg J       Date:  2017-05-01       Impact factor: 4.283

Review 3.  Botulinum toxin the poison that heals: A brief review.

Authors:  Shubha Ranjan Dutta; Deepak Passi; Mahinder Singh; Purnima Singh; Sarang Sharma; Abhimanyu Sharma
Journal:  Natl J Maxillofac Surg       Date:  2016 Jan-Jun

Review 4.  Botulin Toxin Use in Scars/Keloids Treatment.

Authors:  Jacopo Scala; Aleksandra Vojvodic; Petar Vojvodic; Tatjana Vlaskovic-Jovicevic; Zorica Peric-Hajzler; Dusica Matovic; Sanja Dimitrijevic; Jovana Vojvodic; Goran Sijan; Nenad Stepic; Uwe Wollina; Michael Tirant; Nguyen Van Thuong; Massimo Fioranelli; Torello Lotti
Journal:  Open Access Maced J Med Sci       Date:  2019-08-30

Review 5.  Botulinum toxin type A: implications in wound healing, facial cutaneous scarring, and cleft lip repair.

Authors:  Mohammad M Al-Qattan; Bisher Nawras Al-Shanawani; Feras Alshomer
Journal:  Ann Saudi Med       Date:  2013 Sep-Oct       Impact factor: 1.526

  5 in total

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