Literature DB >> 2080860

Effect of heat inactivation of HIV on specific serum proteins and tumour markers.

M Gleeson1, L Herd, C Burns.   

Abstract

The effect on the concentrations of specific serum proteins and tumour markers, of heat-treating samples at 56 degrees C for 30 min to inactivate HIV, was investigated. Statistically significant decreases, that may affect clinical decisions, were observed for alpha-1-antitrypsin, beta-2-microglobulin, IgE, fibrinogen, C1-esterase inhibitor and CA125. Statistical, but not clinically significant, changes were observed for alpha-1-acid glycoprotein, C3, haptoglobin, IgA, IgG, IgM and transferrin. A significant decrease in the alpha-1 band was observed on protein electrophoresis.

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Year:  1990        PMID： 2080860     DOI： 10.1177/000456329002700611

Source DB:  PubMed          Journal:  Ann Clin Biochem        ISSN： 0004-5632            Impact factor:   2.057


  3 in total

1.  Decreased production of local immunoglobulin A to Pneumocystis carinii in bronchoalveolar lavage fluid from human immunodeficiency virus-positive patients.

Authors:  A Jalil; P Moja; C Lambert; M Perol; L Cotte; J M Livrozet; A Boibieux; J M Vergnon; F Lucht; R Tran; C Contini; C Genin
Journal:  Infect Immun       Date:  2000-03       Impact factor: 3.441

2.  Effective chemical virus inactivation of patient serum compatible with accurate serodiagnosis of infections.

Authors:  M M Remy; M Alfter; M-N Chiem; M T Barbani; O B Engler; F Suter-Riniker
Journal:  Clin Microbiol Infect       Date:  2018-10-28       Impact factor: 8.067

3.  TNFRSF13B polymorphisms counter microbial adaptation to enteric IgA.

Authors:  Jeffrey L Platt; Mayara Garcia de Mattos Barbosa; Daniel Huynh; Adam R Lefferts; Juhi Katta; Cyra Kharas; Peter Freddolino; Christine M Bassis; Christiane Wobus; Raif Geha; Richard Bram; Gabriel Nunez; Nobuhiko Kamada; Marilia Cascalho
Journal:  JCI Insight       Date:  2021-07-22
  3 in total

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