Literature DB >> 20807508

Pyruvate carboxylase is expressed in human skeletal muscle.

Ariane D Minet1, Michael Gaster.   

Abstract

Pyruvate carboxylase (PC) is a mitochondrial enzyme that catalyses the carboxylation of pyruvate to oxaloacetate thereby allowing supplementation of citric acid cycle intermediates. The presence of PC in skeletal muscle is controversial. We report here, that PC protein is easily detectable by streptavidin blot and describe the presence of considerable amounts of PC in cultured human myotubes and in human muscle tissue.
Copyright © 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20807508     DOI: 10.1016/j.bbrc.2010.08.102

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  3 in total

1.  Stable isotope tracer analysis in isolated mitochondria from mammalian systems.

Authors:  Simon-Pierre Gravel; Sylvia Andrzejewski; Daina Avizonis; Julie St-Pierre
Journal:  Metabolites       Date:  2014-04-10

Review 2.  Lactate as a Signaling Molecule That Regulates Exercise-Induced Adaptations.

Authors:  Minas Nalbandian; Masaki Takeda
Journal:  Biology (Basel)       Date:  2016-10-08

3.  (13)C metabolic flux analysis shows that resistin impairs the metabolic response to insulin in L6E9 myotubes.

Authors:  Shirley Guzmán; Silvia Marin; Anibal Miranda; Vitaly A Selivanov; Josep J Centelles; Romain Harmancey; Fatima Smih; Annie Turkieh; Yves Durocher; Antonio Zorzano; Philippe Rouet; Marta Cascante
Journal:  BMC Syst Biol       Date:  2014-09-14
  3 in total

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