Literature DB >> 20806052

Insights into neurogenesis and aging: potential therapy for degenerative disease?

Robert A Marr1, Rosanne M Thomas, Daniel A Peterson.   

Abstract

Neurogenesis is the process by which new neural cells are generated from a small population of multipotent stem cells in the adult CNS. This natural generation of new cells is limited in its regenerative capabilities and also declines with age. The use of stem cells in the treatment of neurodegenerative disease may hold great potential; however, the age-related incidence of many CNS diseases coincides with reduced neurogenesis. This review concisely summarizes current knowledge related to adult neurogenesis and its alteration with aging and examines the feasibility of using stem cell and gene therapies to combat diseases of the CNS with advancing age.

Entities:  

Year:  2010        PMID： 20806052      PMCID： PMC2929019          DOI： 10.2217/FNL.10.33

Source DB:  PubMed          Journal:  Future Neurol        ISSN： 1479-6708


  122 in total

Review 1.  Neurogenesis and brain injury: managing a renewable resource for repair.

Authors:  Anna F Hallbergson; Carmen Gnatenco; Daniel A Peterson
Journal:  J Clin Invest       Date:  2003-10       Impact factor: 14.808

2.  Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus.

Authors:  Christoph Schmidt-Hieber; Peter Jonas; Josef Bischofberger
Journal:  Nature       Date:  2004-04-25       Impact factor: 49.962

Review 3.  Guidelines and techniques for the generation of induced pluripotent stem cells.

Authors:  Nimet Maherali; Konrad Hochedlinger
Journal:  Cell Stem Cell       Date:  2008-12-04       Impact factor: 24.633

4.  Age-dependent decline in hippocampal neurogenesis is not altered by chronic treatment with fluoxetine.

Authors:  Daniel S Cowen; Luiz F Takase; Casimir A Fornal; Barry L Jacobs
Journal:  Brain Res       Date:  2008-06-24       Impact factor: 3.252

5.  FGF-2 is sufficient to isolate progenitors found in the adult mammalian spinal cord.

Authors:  L S Shihabuddin; J Ray; F H Gage
Journal:  Exp Neurol       Date:  1997-12       Impact factor: 5.330

6.  Immunolesioning: selective destruction of neurons using immunotoxin to rat NGF receptor.

Authors:  R G Wiley; T N Oeltmann; D A Lappi
Journal:  Brain Res       Date:  1991-10-18       Impact factor: 3.252

7.  Stem/progenitor cell proliferation factors FGF-2, IGF-1, and VEGF exhibit early decline during the course of aging in the hippocampus: role of astrocytes.

Authors:  Ashok K Shetty; Bharathi Hattiangady; Geetha A Shetty
Journal:  Glia       Date:  2005-08-15       Impact factor: 7.452

8.  Targeted transgene expression in neuronal precursors: watching young neurons in the old brain.

Authors:  Sebastien Couillard-Despres; Beate Winner; Claudia Karl; Gudrun Lindemann; Peter Schmid; Robert Aigner; Joern Laemke; Ulrich Bogdahn; Juergen Winkler; Josef Bischofberger; Ludwig Aigner
Journal:  Eur J Neurosci       Date:  2006-09       Impact factor: 3.386

9.  Localized delivery of fibroblast growth factor-2 and brain-derived neurotrophic factor reduces spontaneous seizures in an epilepsy model.

Authors:  Beatrice Paradiso; Peggy Marconi; Silvia Zucchini; Elena Berto; Anna Binaschi; Aleksandra Bozac; Andrea Buzzi; Manuela Mazzuferi; Eros Magri; Graciela Navarro Mora; Donata Rodi; Tao Su; Ilaria Volpi; Lara Zanetti; Andrea Marzola; Roberto Manservigi; Paolo F Fabene; Michele Simonato
Journal:  Proc Natl Acad Sci U S A       Date:  2009-04-06       Impact factor: 11.205

Review 10.  Prospects of stem cell therapy for replacing dopamine neurons in Parkinson's disease.

Authors:  Olle Lindvall; Zaal Kokaia
Journal:  Trends Pharmacol Sci       Date:  2009-04-09       Impact factor: 14.819
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  9 in total

1.  The Ageing Brain: Age-dependent changes in the electroencephalogram during propofol and sevoflurane general anaesthesia.

Authors:  P L Purdon; K J Pavone; O Akeju; A C Smith; A L Sampson; J Lee; D W Zhou; K Solt; E N Brown
Journal:  Br J Anaesth       Date:  2015-07       Impact factor: 9.166

Review 2.  Hippocampal injury-induced cognitive and mood dysfunction, altered neurogenesis, and epilepsy: can early neural stem cell grafting intervention provide protection?

Authors:  Ashok K Shetty
Journal:  Epilepsy Behav       Date:  2014-01-13       Impact factor: 2.937

3.  Water-soluble lipophilic MR contrast agents for cell membrane labeling.

Authors:  Christiane E Carney; Keith W MacRenaris; Thomas J Meade
Journal:  J Biol Inorg Chem       Date:  2015-07-28       Impact factor: 3.358

4.  Neural stem cell grafting counteracts hippocampal injury-mediated impairments in mood, memory, and neurogenesis.

Authors:  Bharathi Hattiangady; Ashok K Shetty
Journal:  Stem Cells Transl Med       Date:  2012-09-05       Impact factor: 6.940

5.  Changes in the Bispectral Index in Response to Loss of Consciousness and No Somatic Movement to Nociceptive Stimuli in Elderly Patients.

Authors:  Ning Yang; Yun Yue; Jonathan Z Pan; Ming-Zhang Zuo; Yu Shi; Shu-Zhen Zhou; Wen-Ping Peng; Jian-Dong Gao
Journal:  Chin Med J (Engl)       Date:  2016-02-20       Impact factor: 2.628

6.  Differential Roles of Environmental Enrichment in Alzheimer's Type of Neurodegeneration and Physiological Aging.

Authors:  Vladimir V Salmin; Yulia K Komleva; Natalia V Kuvacheva; Andrey V Morgun; Elena D Khilazheva; Olga L Lopatina; Elena A Pozhilenkova; Konstantin A Shapovalov; Yulia A Uspenskaya; Alla B Salmina
Journal:  Front Aging Neurosci       Date:  2017-07-26       Impact factor: 5.750

Review 7.  The Impact of Ghrelin in Metabolic Diseases: An Immune Perspective.

Authors:  Jéssica Aparecida da Silva Pereira; Felipe Corrêa da Silva; Pedro Manoel Mendes de Moraes-Vieira
Journal:  J Diabetes Res       Date:  2017-09-07       Impact factor: 4.011

8.  Pharmacological Stimulation of Nurr1 Promotes Cell Cycle Progression in Adult Hippocampal Neural Stem Cells.

Authors:  Haena Moon; Seong Gak Jeon; Jin-Il Kim; Hyeon Soo Kim; Sangho Lee; Dongok Kim; Seungjoon Park; Minho Moon; Hyunju Chung
Journal:  Int J Mol Sci       Date:  2019-12-18       Impact factor: 5.923

9.  Comparison of Bispectral Index-Guided Individualized Anesthesia with Standard General Anesthesia on Inadequate Emergence and Postoperative Delirium in Elderly Patients Undergoing Esophagectomy: A Retrospective Study at a Single Center.

Authors:  Yichen Yang; Chengjun Song; Chengwei Song; Chengwen Li
Journal:  Med Sci Monit       Date:  2020-10-01
  9 in total

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