| Literature DB >> 20804748 |
Abstract
One of the first studies on the energy metabolism of a tumour was carried out, in 1922, in the laboratory of Otto Warburg. He established that cancer cells exhibited a specific metabolic pattern, characterized by a shift from respiration to fermentation, which has been later named the Warburg effect. Considerable work has been done since then, deepening our understanding of the process, with consequences for diagnosis and therapy. This review presents facts and perspectives on the Warburg effect for the 21st century.Entities:
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Year: 2010 PMID: 20804748 DOI: 10.1016/j.yexmp.2010.08.006
Source DB: PubMed Journal: Exp Mol Pathol ISSN: 0014-4800 Impact factor: 3.362