Literature DB >> 20804541

Oxidative stress in obstructive nephropathy.

Amélie Dendooven1, David A Ishola, Tri Q Nguyen, Dionne M Van der Giezen, Robbert Jan Kok, Roel Goldschmeding, Jaap A Joles.   

Abstract

Unilateral ureteric obstruction (UUO) is one of the most commonly applied rodent models to study the pathophysiology of renal fibrosis. This model reflects important aspects of inflammation and fibrosis that are prominent in human kidney diseases. In this review, we present an overview of the factors contributing to the pathophysiology of UUO, highlighting the role of oxidative stress.
© 2010 The Authors. International Journal of Experimental Pathology © 2010 International Journal of Experimental Pathology.

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Year:  2010        PMID： 20804541      PMCID： PMC3101492          DOI： 10.1111/j.1365-2613.2010.00730.x

Source DB:  PubMed          Journal:  Int J Exp Pathol        ISSN： 0959-9673            Impact factor:   1.925


  132 in total

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  43 in total

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