Xin Ying1, Zhen-ya Song, Chang-jun Zhao, Yan Jiang. 1. International Health Care Center, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China. yingxin1977@gmail.com
Abstract
OBJECTIVE: To assess the associations between body mass index (BMI), waist circumference (WC), and cardiometabolic risk factors in young and middle-aged Chinese women. METHODS: A total of 3011 women (1938 young women, 1073 middle-aged women), who visited our health care center for a related health checkup, were eligible for study. BMI and WC were measured. The subjects were divided into normal and overweight/obesity groups based on BMI, and normal and abdominal obesity groups based on WC. Cardiometabolic variables included triglyceride (TG), high density lipoprotein cholesterol (HDL-C), fasting blood glucose (FBG), homeostasis model assessment of insulin resistance (HOMA-IR), and blood pressure (BP). RESULTS: The prevalence of overweight/obesity was significantly higher in middle-aged women (32.4%) than in young women (12.0%). The prevalence of abdominal obesity was also higher in middle-aged women (60.3%) than in young women (36.2%). There were significant differences in the comparison of all related cardiometabolic variables between different BMI (or WC) categories in young and middle- aged women groups, respectively. After adjustment for age, partial correlation analysis indicated that both BMI and WC were correlated significantly with all related cardiometabolic variables. After adjustment for age and WC, although the correlation coefficient r' was attenuated, BMI was still correlated significantly with all related cardiometabolic variables in young and middle-aged women. After adjustment for age and BMI, partial correlation analysis showed that WC was correlated significantly with TG, FBG, HOMA-IR, and HDL-C in young women and significantly with TG, HOMA-IR, and HDL-C in middle-aged women. CONCLUSIONS: The prevalence of overweight/obesity and abdominal obesity was high in Chinese young and middle-aged women. BMI was a better predictor of cardiovascular disease and diabetes than WC in young and middle-aged women, and moreover, measurement of both WC and BMI may be a better predictor of cardiovascular disease and diabetes mellitus than BMI or WC alone.
OBJECTIVE: To assess the associations between body mass index (BMI), waist circumference (WC), and cardiometabolic risk factors in young and middle-aged Chinese women. METHODS: A total of 3011 women (1938 young women, 1073 middle-aged women), who visited our health care center for a related health checkup, were eligible for study. BMI and WC were measured. The subjects were divided into normal and overweight/obesity groups based on BMI, and normal and abdominal obesity groups based on WC. Cardiometabolic variables included triglyceride (TG), high density lipoprotein cholesterol (HDL-C), fasting blood glucose (FBG), homeostasis model assessment of insulin resistance (HOMA-IR), and blood pressure (BP). RESULTS: The prevalence of overweight/obesity was significantly higher in middle-aged women (32.4%) than in young women (12.0%). The prevalence of abdominal obesity was also higher in middle-aged women (60.3%) than in young women (36.2%). There were significant differences in the comparison of all related cardiometabolic variables between different BMI (or WC) categories in young and middle- aged women groups, respectively. After adjustment for age, partial correlation analysis indicated that both BMI and WC were correlated significantly with all related cardiometabolic variables. After adjustment for age and WC, although the correlation coefficient r' was attenuated, BMI was still correlated significantly with all related cardiometabolic variables in young and middle-aged women. After adjustment for age and BMI, partial correlation analysis showed that WC was correlated significantly with TG, FBG, HOMA-IR, and HDL-C in young women and significantly with TG, HOMA-IR, and HDL-C in middle-aged women. CONCLUSIONS: The prevalence of overweight/obesity and abdominal obesity was high in Chinese young and middle-aged women. BMI was a better predictor of cardiovascular disease and diabetes than WC in young and middle-aged women, and moreover, measurement of both WC and BMI may be a better predictor of cardiovascular disease and diabetes mellitus than BMI or WC alone.
Authors: Ali H Mokdad; Earl S Ford; Barbara A Bowman; William H Dietz; Frank Vinicor; Virginia S Bales; James S Marks Journal: JAMA Date: 2003-01-01 Impact factor: 56.272
Authors: Yao He; Tai Hing Lam; Bin Jiang; Jie Wang; Xiaoyong Sai; Li Fan; Xiaoying Li; Yinhe Qin; Frank B Hu Journal: Circulation Date: 2008-09-22 Impact factor: 29.690
Authors: Cynthia L Ogden; Margaret D Carroll; Lester R Curtin; Margaret A McDowell; Carolyn J Tabak; Katherine M Flegal Journal: JAMA Date: 2006-04-05 Impact factor: 56.272
Authors: Beverley Balkau; John E Deanfield; Jean-Pierre Després; Jean-Pierre Bassand; Keith A A Fox; Sidney C Smith; Philip Barter; Chee-Eng Tan; Luc Van Gaal; Hans-Ulrich Wittchen; Christine Massien; Steven M Haffner Journal: Circulation Date: 2007-10-23 Impact factor: 29.690
Authors: Merle R Kataoka-Yahiro; Kamomilani Anduha Wong; Jill Tamashiro; Victoria Page; Julaine Ching; Dongmei Li Journal: Hawaii J Med Public Health Date: 2012-07
Authors: Chidozie U Nduka; Olalekan A Uthman; Peter K Kimani; Abraham O Malu; Saverio Stranges Journal: Infect Dis Poverty Date: 2016-06-01 Impact factor: 4.520
Authors: Nayla Cristina do Vale Moreira; Ibrahimu Mdala; Akhtar Hussain; Bishwajit Bhowmik; Tasnima Siddiquee; Virgínia Oliveira Fernandes; Renan M Montenegro; Haakon E Meyer Journal: Front Public Health Date: 2021-11-30