Literature DB >> 20803590

Addressing protein-protein interactions with small molecules: a Pro-Pro dipeptide mimic with a PPII helix conformation as a module for the synthesis of PRD-binding ligands.

Jan Zaminer1, Christoph Brockmann, Peter Huy, Robert Opitz, Cédric Reuter, Michael Beyermann, Christian Freund, Matthias Müller, Hartmut Oschkinat, Ronald Kühne, Hans-Günther Schmalz.   

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Year:  2010        PMID： 20803590     DOI： 10.1002/anie.201001739

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  9 in total

1.  A modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions.

Authors:  Robert Opitz; Matthias Müller; Cédric Reuter; Matthias Barone; Arne Soicke; Yvette Roske; Kirill Piotukh; Peter Huy; Monika Beerbaum; Burkhard Wiesner; Michael Beyermann; Peter Schmieder; Christian Freund; Rudolf Volkmer; Hartmut Oschkinat; Hans-Günther Schmalz; Ronald Kühne
Journal:  Proc Natl Acad Sci U S A       Date:  2015-04-06       Impact factor: 11.205

2.  Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.

Authors:  Matthias Barone; Matthias Müller; Slim Chiha; Jiang Ren; Dominik Albat; Arne Soicke; Stephan Dohmen; Marco Klein; Judith Bruns; Maarten van Dinther; Robert Opitz; Peter Lindemann; Monika Beerbaum; Kathrin Motzny; Yvette Roske; Peter Schmieder; Rudolf Volkmer; Marc Nazaré; Udo Heinemann; Hartmut Oschkinat; Peter Ten Dijke; Hans-Günther Schmalz; Ronald Kühne
Journal:  Proc Natl Acad Sci U S A       Date:  2020-11-12       Impact factor: 11.205

3.  Synthetic α-Helical Peptides as Potential Inhibitors of the ACE2 SARS-CoV-2 Interaction.

Authors:  Pascal M Engelhardt; Sebastián Florez-Rueda; Marco Drexelius; Jörg-Martin Neudörfl; Daniel Lauster; Christian P R Hackenberger; Ronald Kühne; Ines Neundorf; Hans-Günther Schmalz
Journal:  Chembiochem       Date:  2022-07-14       Impact factor: 3.461

4.  Identification of Δ-1-pyrroline-5-carboxylate derived biomarkers for hyperprolinemia type II.

Authors:  Jona Merx; Rianne E van Outersterp; Udo F H Engelke; Veronique Hendriks; Ron A Wevers; Marleen C D G Huigen; Huub W A H Waterval; Irene M L W Körver-Keularts; Jasmin Mecinović; Floris P J T Rutjes; Jos Oomens; Karlien L M Coene; Jonathan Martens; Thomas J Boltje
Journal:  Commun Biol       Date:  2022-09-21

5.  A new entry to azomethine ylides from allylic amines and glyoxals: shifting the reliance on amino ester precursors.

Authors:  Natalie K Machamer; Xiaoxi Liu; Stephen P Waters
Journal:  Org Lett       Date:  2014-09-23       Impact factor: 6.005

6.  Triple-Helix-Stabilizing Effects in Collagen Model Peptides Containing PPII-Helix-Preorganized Diproline Modules.

Authors:  Andreas Maaßen; Jan M Gebauer; Elena Theres Abraham; Isabelle Grimm; Jörg-Martin Neudörfl; Ronald Kühne; Ines Neundorf; Ulrich Baumann; Hans-Günther Schmalz
Journal:  Angew Chem Int Ed Engl       Date:  2020-02-03       Impact factor: 15.336

7.  Pd-Catalyzed Asymmetric N-Allylation of Amino Acid Esters with Exceptional Levels of Catalyst Control: Stereo-Divergent Synthesis of ProM-15 and Related Bicyclic Dipeptide Mimetics.

Authors:  Stephan Dohmen; Martin Reiher; Dominik Albat; Sema Akyol; Matthias Barone; Jörg-Martin Neudörfl; Ronald Kühne; Hans-Günther Schmalz
Journal:  Chemistry       Date:  2020-02-18       Impact factor: 5.236

8.  Stafia-1: a STAT5a-Selective Inhibitor Developed via Docking-Based Screening of in Silico O-Phosphorylated Fragments.

Authors:  Kalaiselvi Natarajan; Daniel Müller-Klieser; Stefan Rubner; Thorsten Berg
Journal:  Chemistry       Date:  2019-11-27       Impact factor: 5.236

9.  Non-natural 3-Arylmorpholino-β-amino Acid as a PPII Helix Inducer.

Authors:  Francesco Vaghi; Raffaella Bucci; Francesca Clerici; Alessandro Contini; M Luisa Gelmi
Journal:  Org Lett       Date:  2020-07-30       Impact factor: 6.005
  9 in total

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