Literature DB >> 20801665

Excitation function for deuteron induced nuclear reactions on natural ytterbium for production of high specific activity 177g Lu in no-carrier-added form for metabolic radiotherapy.

Simone Manenti1, Flavia Groppi, Andrea Gandini, Luigi Gini, Kamel Abbas, Uwe Holzwarth, Federica Simonelli, Mauro Bonardi.   

Abstract

Deuteron-induced nuclear reactions for generation of no-carrier-added Lu radionuclides were investigated using the stacked-foil activation technique on natural Yb targets at energies up to E(d)=18.18 MeV. Excitation functions of the reactions (nat)Yb(d,xn)(169,170,171,172,173,174g,174m,176m,177g)Lu and (nat)Yb(d,pxn)(169,175,177)Yb have been measured, among them three ((169)Lu, (174m)Lu and (176m)Lu) are reported for the first time. The upper limit of the contamination from the long-lived metastable level (177m)Lu was evaluated too. Thick-target yields for all investigated radionuclides are calculated.
Copyright © 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20801665     DOI: 10.1016/j.apradiso.2010.08.008

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  4 in total

Review 1.  Production of (177)Lu for Targeted Radionuclide Therapy: Available Options.

Authors:  Ashutosh Dash; Maroor Raghavan Ambikalmajan Pillai; Furn F Knapp
Journal:  Nucl Med Mol Imaging       Date:  2015-02-17

Review 2.  A review of advances in the last decade on targeted cancer therapy using 177Lu: focusing on 177Lu produced by the direct neutron activation route.

Authors:  Rubel Chakravarty; Sudipta Chakraborty
Journal:  Am J Nucl Med Mol Imaging       Date:  2021-12-15

3.  Recovery of 177Lu from Irradiated HfO2 Targets for Nuclear Medicine Purposes.

Authors:  Andrey G Kazakov; Taisya Y Ekatova; Julia S Babenya; Sergey S Belyshev; Vadim V Khankin; Alexander A Kuznetsov; Sergey E Vinokurov; Boris F Myasoedov
Journal:  Molecules       Date:  2022-05-16       Impact factor: 4.927

Review 4.  Matrices and Affinity Ligands for Antibody Purification and Corresponding Applications in Radiotherapy.

Authors:  Aiying Xue; Saijun Fan
Journal:  Biomolecules       Date:  2022-06-12
  4 in total

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