Literature DB >> 20800458

Palliation of male genital cancers.

C J Shukla1, M Shabbir, M R Feneley, S Withey, A Muneer, S Minhas.   

Abstract

Advanced genital tumours are rare. Traditionally, surgical intervention in these patients has had a limited role due to the associated co-morbidities, poor performance status and overall poor prognosis. Because the potential benefit of surgical intervention in advanced cases is not evidence based, a large proportion of these patients are treated palliatively with chemoradiation therapy, which may have a limited role in advanced disease together with no significant improvement in quality of life for the patient. We present a review of palliative surgical techniques and non-surgical interventions in a range of male genital malignancies. Although the focus relates to advanced tumours with a palliative intent, a brief discussion on treatment with a view to cure is also covered. The traditional dogma is challenged with demonstration of value in surgery as part of multimodal therapy. Various surgical techniques that are used not only to excise the primary tumour, but also those of reconstruction of the urinary tract as well as techniques of flap and graft-based coverage are described. We show the essential role of surgery as part of multimodal therapy in well-motivated patients. No longer is surgery considered as having a limited role in these patients with advanced male genital malignancy.
Copyright © 2010 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20800458     DOI: 10.1016/j.clon.2010.07.010

Source DB:  PubMed          Journal:  Clin Oncol (R Coll Radiol)        ISSN: 0936-6555            Impact factor:   4.126


  2 in total

Review 1.  Challenges and controversies in the management of penile cancer.

Authors:  Majid Shabbir; Oliver Kayes; Suks Minhas
Journal:  Nat Rev Urol       Date:  2014-11-18       Impact factor: 14.432

2.  Long-term outcomes for penile cancer patients presenting with advanced N3 disease requiring a myocutaneous flap reconstruction or primary closure-a retrospective single centre study.

Authors:  Hussain M Alnajjar; Findlay MacAskill; Michelle Christodoulidou; Ash Mosahebi; Clare Akers; Raj Nigam; Peter Malone; David Ralph; Anita Mitra; Asif Muneer
Journal:  Transl Androl Urol       Date:  2019-03
  2 in total

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