| Literature DB >> 2080005 |
A Rashed1, B Azadeh, S H Abu Romeh.
Abstract
Two patients with presumed herpes simplex encephalitis developed severe non-oliguric acute renal failure shortly after acyclovir infusions. Renal function returned to normal in less than 3 weeks after discontinuation of acyclovir. Renal biopsies done during the acute phase demonstrated interstitial oedema, eosinophils and cellular aggregates in both and granulomata in the second case suggesting acyclovir-induced hypersensitivity interstitial nephritis.Entities:
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Year: 1990 PMID： 2080005 DOI： 10.1159/000186190
Source DB: PubMed Journal: Nephron ISSN： 1660-8151 Impact factor: 2.847