Literature DB >> 20798954

Fyodorov-Zuev keratoprosthesis implantation: long-term results in patients with multiple failed corneal grafts.

Alireza Ghaffariyeh1, Nazafarin Honarpisheh, Akbar Karkhaneh, Reza Abudi, Zinaida Ivanovna Moroz, Alireza Peyman, Abolhasan Faramarzi, Fuad Abasov.   

Abstract

BACKGROUND: The long term results of the Fyodorov-Zuev keratoprosthesis are presented for ten patients with repeated graft failures.
METHODS: The study took place at Dr Khodadoust Eye Hospital. The Fyodorov-Zuev keratoprosthesis was implanted in ten patients with repeated graft failures, including seven patients with old trachoma, two patients with chemical injury, and a patient with thermal injury. The outcome measures were visual acuity, retention, and complications of the keratoprosthesis.
RESULTS: Preoperative best-uncorrected visual acuity (BUVA) ranged from counting fingers to light perception (median: light perception). The keratoprosthesis dramatically improved vision in most patients. Patients retained BUVA of 20/200-20/50 in 50%, 20/60-20/100 in 30%, 20/200 in 10% and 20/400 in 10%. Overall, 90% had 1 year postoperative vision of 20/200 or better. 70% of cases had BUVA of 20/200 or better at the last follow-up (average 52 months). Of ten keratoprosthesis implanted, three have been removed, and as a result, retention rate was 70% during average follow-up of 52 months .The most common postoperative complications were retroprosthetic membrane formation (40%), uveitis (20%), glaucoma (20%), tissue overgrowth (20%), early leakage (20%), late leakage (20%), aseptic necrosis (20%), retinal detachment (10%), endophthalmitis (10%), and granulation tissue growth (10%).
CONCLUSIONS: Fyodorov-Zuev keratoprosthesis is an effective means of managing repeated corneal graft failure.

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Year:  2010        PMID: 20798954     DOI: 10.1007/s00417-010-1493-8

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.117


  24 in total

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