OBJECTIVES: There is growing evidence for an adverse effect of maternal exposure to air pollution on pregnancy outcomes. As European data on this topic are limited, the aim of this study was to evaluate the impact of maternal exposure to traffic-related air pollution during different periods of pregnancy on preterm birth and fetal growth. METHODS: We estimated maternal residential exposure to NO(2) during pregnancy (entire pregnancy and trimesters) for 7600 singleton births participating in the Amsterdam Born Children and their Development (ABCD) prospective birth cohort study by means of a temporally adjusted land-use regression model. Associations between air pollution concentrations and preterm birth and fetal growth (expressed as small for gestational age and term birth weight) were analysed by means of logistic and linear regression models with and without adjustment for maternal physiological, lifestyle and sociodemographic characteristics. RESULTS: There was no indication of an increase in preterm birth among highly exposed women. Children of mothers with NO(2) levels in the highest exposure category on average had the highest term birth weight of all children and were among those with the lowest risk of being small for gestational age with little indication of a dose-response relationship. CONCLUSIONS: In this study, there is no evidence for a harmful effect of estimated maternal exposure to traffic-related air pollution during pregnancy on pregnancy outcomes such as preterm birth, small for gestational age and term birth weight.
OBJECTIVES: There is growing evidence for an adverse effect of maternal exposure to air pollution on pregnancy outcomes. As European data on this topic are limited, the aim of this study was to evaluate the impact of maternal exposure to traffic-related air pollution during different periods of pregnancy on preterm birth and fetal growth. METHODS: We estimated maternal residential exposure to NO(2) during pregnancy (entire pregnancy and trimesters) for 7600 singleton births participating in the Amsterdam Born Children and their Development (ABCD) prospective birth cohort study by means of a temporally adjusted land-use regression model. Associations between air pollution concentrations and preterm birth and fetal growth (expressed as small for gestational age and term birth weight) were analysed by means of logistic and linear regression models with and without adjustment for maternal physiological, lifestyle and sociodemographic characteristics. RESULTS: There was no indication of an increase in preterm birth among highly exposed women. Children of mothers with NO(2) levels in the highest exposure category on average had the highest term birth weight of all children and were among those with the lowest risk of being small for gestational age with little indication of a dose-response relationship. CONCLUSIONS: In this study, there is no evidence for a harmful effect of estimated maternal exposure to traffic-related air pollution during pregnancy on pregnancy outcomes such as preterm birth, small for gestational age and term birth weight.
Authors: Hamisu M Salihu; Euna M August; Alfred K Mbah; Amina P Alio; Raymond de Cuba; Foday M Jaward; Estrellita Lo Berry Journal: Matern Child Health J Date: 2012-11
Authors: Beate Ritz; Jiaheng Qiu; Pei-Chen Lee; Fred Lurmann; Bryan Penfold; Robert Erin Weiss; Rob McConnell; Chander Arora; Calvin Hobel; Michelle Wilhelm Journal: Environ Res Date: 2014-02-08 Impact factor: 6.498
Authors: Jo Kay C Ghosh; Michelle Wilhelm; Jason Su; Daniel Goldberg; Myles Cockburn; Michael Jerrett; Beate Ritz Journal: Am J Epidemiol Date: 2012-05-13 Impact factor: 4.897
Authors: Michelle Wilhelm; Jo Kay Ghosh; Jason Su; Myles Cockburn; Michael Jerrett; Beate Ritz Journal: Environ Health Perspect Date: 2011-08-11 Impact factor: 9.031