Literature DB >> 20797943

Relationship between severity of symptoms and quality of life in patients with breast cancer receiving adjuvant hormonal therapy.

Leah Ochayon1, Revital Zelker, Luna Kaduri, Ilana Kadmon.   

Abstract

PURPOSE/
OBJECTIVES: To describe symptoms and quality of life (QOL) of patients with breast cancer receiving adjuvant hormonal therapy and to examine possible relationships between the two measurements.
DESIGN: Descriptive, correlational study.
SETTING: An oncology clinic within a tertiary medical center in Israel. SAMPLE: Convenience sample of 132 patients diagnosed with primary breast cancer receiving hormonal therapy.
METHODS: Data collection was conducted through the self-administered Functional Assessment of Cancer Therapy endocrine subscale and a sociodemographic and medical information questionnaire. MAIN RESEARCH VARIABLES: QOL and symptoms of hormonal therapy.
FINDINGS: Ten symptoms were categorized by more than 20% of the participants as "very much" or "quite a bit." The mean QOL score for the participants was higher than that for a healthy population, although a correlation was found between fewer symptoms and higher QOL. Mood swings and irritability were the symptoms most strongly associated with a decrease in QOL. Patients who exercised had higher QOL scores.
CONCLUSIONS: Adjuvant hormonal therapy did not affect the QOL of a majority of patients with primary breast cancer. A reduced number of symptoms indicated a higher QOL. Mood swings and irritability have a negative impact on QOL. IMPLICATIONS FOR NURSING: A need exists to design a program to follow up on hormonal symptoms and the QOL of patients receiving hormonal therapy and to encourage patients to engage in regular exercise.

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Year:  2010        PMID: 20797943     DOI: 10.1188/10.ONF.E349-E358

Source DB:  PubMed          Journal:  Oncol Nurs Forum        ISSN: 0190-535X            Impact factor:   2.172


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