| Literature DB >> 20797709 |
Mariona Rius1, Gemma Daina, Albert Obradors, Laia Ramos, Esther Velilla, Sílvia Fernández, Olga Martínez-Passarell, Jordi Benet, Joaquima Navarro.
Abstract
The short comparative genomic hybridization (short-CGH) method was used to perform a comprehensive cytogenetic study of isolated blastomeres from advanced maternal age embryos, discarded after fluorescent in situ hybridization (FISH) preimplantation genetic screening (PGS), detecting aneuploidies (38.5% of which corresponded to chromosomes not screened by 9-chromosome FISH), structural aberrations (31.8%), and mosaicism (77.3%). The short-CGH method was subsequently applied in one PGS, achieving a twin pregnancy.Entities:
Mesh：
Year: 2010 PMID： 20797709 DOI： 10.1016/j.fertnstert.2010.07.1051
Source DB: PubMed Journal: Fertil Steril ISSN： 0015-0282 Impact factor: 7.329