Literature DB >> 2079641

Hydantoin derivatives. A new class of inhibitors of human leukocyte elastase.

W C Groutas1, M A Stanga, J C Castrisos, E J Schatz.   

Abstract

Derivatives of hydantoin have been found to inactivate human leukocyte elastase irreversibly. Chymotrypsin and cathepsin G are also inhibited by these compounds.

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Year:  1990        PMID： 2079641     DOI： 10.3109/14756369009035842

Source DB:  PubMed          Journal:  J Enzyme Inhib        ISSN： 1026-5457


  1 in total

1.  Use of the hydantoin isostere to produce inhibitors showing selectivity toward the vesicular glutamate transporter versus the obligate exchange transporter system x(c)(-).

Authors:  S Kaleem Ahmed; Jean-Louis G Etoga; Sarjubhai A Patel; Richard J Bridges; Charles M Thompson
Journal:  Bioorg Med Chem Lett       Date:  2011-05-14       Impact factor: 2.823
  1 in total

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