OBJECTIVE: To develop clinical risk tools for preeclampsia and small for gestational age (SGA) in high-risk women. METHODS:Individual risk scores based on clinical risk factors were calculated using logistic regression and validated in 1687 women with obesity in first pregnancy, chronic hypertension, or previous preeclampsia. RESULTS: The risk of preeclampsia varied from 7% in obese primiparae without hypertension to 30% when previous preeclampsia and chronic hypertension occurred together. A prediction model incorporating these risk factors had a sensitivity of 48 and 89% for preeclampsia delivered <34 weeks' gestation. CONCLUSION: Multiple clinical risk factors increase the risk of preeclampsia and SGA.
RCT Entities:
OBJECTIVE: To develop clinical risk tools for preeclampsia and small for gestational age (SGA) in high-risk women. METHODS: Individual risk scores based on clinical risk factors were calculated using logistic regression and validated in 1687 women with obesity in first pregnancy, chronic hypertension, or previous preeclampsia. RESULTS: The risk of preeclampsia varied from 7% in obese primiparae without hypertension to 30% when previous preeclampsia and chronic hypertension occurred together. A prediction model incorporating these risk factors had a sensitivity of 48 and 89% for preeclampsia delivered <34 weeks' gestation. CONCLUSION: Multiple clinical risk factors increase the risk of preeclampsia and SGA.
Authors: David M Haas; Corette B Parker; Deborah A Wing; Samuel Parry; William A Grobman; Brian M Mercer; Hyagriv N Simhan; Matthew K Hoffman; Robert M Silver; Pathik Wadhwa; Jay D Iams; Matthew A Koch; Steve N Caritis; Ronald J Wapner; M Sean Esplin; Michal A Elovitz; Tatiana Foroud; Alan M Peaceman; George R Saade; Marian Willinger; Uma M Reddy Journal: Am J Obstet Gynecol Date: 2015-01-31 Impact factor: 8.661
Authors: Lje Meertens; Ljm Smits; Smj van Kuijk; R Aardenburg; Ima van Dooren; J Langenveld; I M Zwaan; Mea Spaanderman; Hcj Scheepers Journal: BJOG Date: 2019-01-17 Impact factor: 6.531