Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 An efficient synthesis of hydantoins via sustainable integration of coupled domino processes.

Literature DB >> 20795705

An efficient synthesis of hydantoins via sustainable integration of coupled domino processes.

Meng Gao¹, Yan Yang, Yan-Dong Wu, Cong Deng, Wen-Ming Shu, Dong-Xue Zhang, Li-Ping Cao, Neng-Fang She, An-Xin Wu.

Abstract

A highly efficient synthesis of hydantoins has been developed from simple and commercially available 1,3-dicarbonyl compounds, ureas, and methyl ketones or terminal aryl alkenes. This protocol involves a sustainable integration of two coupled domino processes: iodine-promoted synthesis of unsymmetrical 1,4-enediones (domino I) and the sequential transformation into hydantoins (domino II).

Entities: Chemical

Year: 2010 PMID： 20795705 DOI： 10.1021/ol1015948

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

Keyword Cloud
Cited

5 in total

1. Iodine-mediated sp³ C-H functionalization of methyl ketones: a one-pot synthesis of functionalized indolizines via the 1,3-dipolar cycloaddition reaction between pyridinium ylides and ynones.

Authors: Issa Yavari; Jamil Sheykhahmadi; Maryam Naeimabadi; Mohammad Reza Halvagar
Journal: Mol Divers Date: 2017-01-11 Impact factor: 2.943

2. Parallel Solid-Phase Synthesis of disubstituted 3-(1H-benzo[d]imidazol-2-yl)imidazolidine-2,4-diones and 3-(1H-benzo[d]imidazol-2-yl)-2-thioxoimidazolidin-4-ones.

Authors: Sureshbabu Dadiboyena; Adel Nefzi
Journal: Tetrahedron Lett Date: 2011-12-28 Impact factor: 2.415

An efficient synthesis of hydantoins via sustainable integration of coupled domino processes.

1. Iodine-mediated sp³ C-H functionalization of methyl ketones: a one-pot synthesis of functionalized indolizines via the 1,3-dipolar cycloaddition reaction between pyridinium ylides and ynones.

2. Parallel Solid-Phase Synthesis of disubstituted 3-(1H-benzo[d]imidazol-2-yl)imidazolidine-2,4-diones and 3-(1H-benzo[d]imidazol-2-yl)-2-thioxoimidazolidin-4-ones.

3. Methyl 3-(4-chloro-phen-yl)-2-(1,3-dimethyl-2,5-dioxo-4-phenyl-imidazolidin-4-yl)-3-oxopropano-ate.

4. One-Flask Synthesis of Pyrazolo[3,4-d]pyrimidines from 5-Aminopyrazoles and Mechanistic Study.

5. Cu-catalyzed N-3-Arylation of Hydantoins Using Diaryliodonium Salts.