Literature DB >> 2079376

[Therapy of pediatric infections with cefixime].

H Helwig1.   

Abstract

In a pilot study with a limited number of patients the efficacy and tolerance of cefixime, a new oral cephalosporin antibiotic, were investigated in 15 children with the clinical diagnosis of bacterial respiratory tract infection, otitis media or urinary tract infection. The dosage was 2 x 4 mg/kg body weight daily for a period of seven to 11 days. Clinical efficacy was good in 13 cases, and subjective tolerance was good in all cases. The results support the assumption that cefixime is suited for the treatment of children with bacterial infections of the airways and urinary tract with sensitive pathogens.

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Year:  1990        PMID: 2079376     DOI: 10.1007/BF01644635

Source DB:  PubMed          Journal:  Infection        ISSN: 0300-8126            Impact factor:   3.553


  8 in total

1.  Safety profile of cefixime.

Authors:  F P Tally; R E Desjardins; E F McCarthy; K Cartwright
Journal:  Pediatr Infect Dis J       Date:  1987-10       Impact factor: 2.129

2.  Randomized, open label, multicenter trial of cefixime compared with amoxicillin for treatment of acute otitis media with effusion.

Authors:  S E McLinn
Journal:  Pediatr Infect Dis J       Date:  1987-10       Impact factor: 2.129

3.  Noncomparative, open label, multicenter trial of cefixime for treatment of bacterial pharyngitis, cystitis and pneumonia in pediatric patients.

Authors:  W L Risser; J S Barone; P A Clark; D L Simpkins
Journal:  Pediatr Infect Dis J       Date:  1987-10       Impact factor: 2.129

4.  Pharmacokinetic profile of cefixime in man.

Authors:  R D Faulkner; A Yacobi; J S Barone; S A Kaplan; B M Silber
Journal:  Pediatr Infect Dis J       Date:  1987-10       Impact factor: 2.129

5.  In vitro activity of a new broad spectrum, beta-lactamase-stable oral cephalosporin, cefixime.

Authors:  H C Neu
Journal:  Pediatr Infect Dis J       Date:  1987-10       Impact factor: 2.129

6.  Cefixime: spectrum of antibacterial activity against 16,016 clinical isolates.

Authors:  A L Barry; R N Jones
Journal:  Pediatr Infect Dis J       Date:  1987-10       Impact factor: 2.129

7.  Bacteriologic and clinical efficacy of cefixime compared with amoxicillin in acute otitis media.

Authors:  V M Howie; M J Owen
Journal:  Pediatr Infect Dis J       Date:  1987-10       Impact factor: 2.129

8.  Cefixime vs. cefaclor in the treatment of acute otitis media in infants and children.

Authors:  M A Kenna; C D Bluestone; P Fall; J Stephenson; M Kurs-Lasky; F P Wucher; M M Blatter; K S Reisinger
Journal:  Pediatr Infect Dis J       Date:  1987-10       Impact factor: 2.129

  8 in total

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