Literature DB >> 2079375

[Cefixime therapy in patients with proven gonorrhea].

A Backhaus, J Tinzl.   

Abstract

Cefixime is a new third generation oral cephalosporin that exhibits excellent antibacterial activity against Neisseria gonorrhoeae, including beta-lactamase-positive strains. In an open uncontrolled clinical trial 14 male patients suffering from acute gonorrhea, aged 23 to 48 years, were treated with a single dose of 400 mg of cefixime. All 13 fully evaluable patients were clinically and bacteriologically cured. Side effects were not reported.

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Year:  1990        PMID: 2079375     DOI: 10.1007/BF01644634

Source DB:  PubMed          Journal:  Infection        ISSN: 0300-8126            Impact factor:   3.553


  4 in total

1.  In vitro activity of difloxacin hydrochloride (A-56619), A-56620, and cefixime (CL 284,635; FK 027) against selected genital pathogens.

Authors:  W R Bowie; C E Shaw; D G Chan; J Boyd; W A Black
Journal:  Antimicrob Agents Chemother       Date:  1986-10       Impact factor: 5.191

2.  Efficacy and safety of a single 400 mg oral dose of cefixime in the treatment of uncomplicated gonorrhea.

Authors:  A Kuhlwein; B A Nies
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1989-03       Impact factor: 3.267

3.  Cefixime, in-vitro activity, pharmacokinetics and tissue penetration.

Authors:  J W Stone; G Linong; J M Andrews; R Wise
Journal:  J Antimicrob Chemother       Date:  1989-02       Impact factor: 5.790

4.  Cefixime: spectrum of antibacterial activity against 16,016 clinical isolates.

Authors:  A L Barry; R N Jones
Journal:  Pediatr Infect Dis J       Date:  1987-10       Impact factor: 2.129

  4 in total
  1 in total

1.  Single dose oral administration of cefixime 400mg in the treatment of acute uncomplicated cystitis and gonorrhoea.

Authors:  H W Asbach
Journal:  Drugs       Date:  1991       Impact factor: 9.546

  1 in total

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