Literature DB >> 2078813

Sex-related differences and thyroid hormone regulation of vasoactive intestinal peptide gene expression in the rat brain and pituitary.

K S Lam1, G Srivastava.   

Abstract

To determine the effects of hypothyroidism and sexual dimorphism on the gene expression of vasoactive intestinal peptide (VIP) in the rat brain, VIP mRNA levels were measured in the cerebral cortex, hypothalamus and anterior pituitary of control and hypothyroid (thionamide-treated) rats. A tissue-specific increase in VIP mRNA level was observed in the hypothyroid pituitary. In addition, higher levels of VIP mRNA were found in the pituitaries of male rats suggesting a sex-related difference in VIP gene expression. Similar differences were not observed in the cortex or hypothalamus.

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Year:  1990        PMID： 2078813     DOI： 10.1016/0006-8993(90)90259-e

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  4 in total

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Journal:  J Mol Neurosci       Date:  2018-06-07       Impact factor: 3.444

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Journal:  PLoS One       Date:  2015-09-29       Impact factor: 3.240

4.  VPAC1 receptors play a dominant role in PACAP-induced vasorelaxation in female mice.

Authors:  Ivan Ivic; Marta Balasko; Balazs D Fulop; Hitoshi Hashimoto; Gabor Toth; Andrea Tamas; Tamas Juhasz; Akos Koller; Dora Reglodi; Margit Solymár
Journal:  PLoS One       Date:  2019-01-25       Impact factor: 3.240
  4 in total

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