Literature DB >> 2078279

Neuropsychiatric disorders and the multiple human brain serotonin receptor subtypes and subsystems.

D L Murphy1.   

Abstract

Most evaluations of the contributions of possible alterations in serotonergic neurotransmission to the etiology and treatment of neuropsychiatric disorders preceded the recent explosion of information regarding multiple serotonin (5-HT) receptors and brain 5-HT subsystems. This review provides an appraisal of some examples where drugs acting at different 5-HT receptor subtypes have provided new treatment or have contributed to the development of knowledge regarding various neuropsychiatric disorders, including anxiety, panic disorder, obsessive-compulsive disorder, depression, schizophrenia, alcoholism, migraine, sexual dysfunction, and Alzheimer's disease.

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Year:  1990        PMID： 2078279

Source DB:  PubMed          Journal:  Neuropsychopharmacology        ISSN： 0893-133X            Impact factor:   7.853


  9 in total

1.  Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype.

Authors:  G McAllister; A Charlesworth; C Snodin; M S Beer; A J Noble; D N Middlemiss; L L Iversen; P Whiting
Journal:  Proc Natl Acad Sci U S A       Date:  1992-06-15       Impact factor: 11.205

2.  Increased anxiety of mice lacking the serotonin1A receptor.

Authors:  C L Parks; P S Robinson; E Sibille; T Shenk; M Toth
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-01       Impact factor: 11.205

Review 3.  The Black Book of Psychotropic Dosing and Monitoring.

Authors:  Alan F Schatzberg; DeBattista Charles
Journal:  Psychopharmacol Bull       Date:  2018-01-15

4.  Genetic inactivation of the Serotonin(1A) receptor in mice results in downregulation of major GABA(A) receptor alpha subunits, reduction of GABA(A) receptor binding, and benzodiazepine-resistant anxiety.

Authors:  E Sibille; C Pavlides; D Benke; M Toth
Journal:  J Neurosci       Date:  2000-04-15       Impact factor: 6.167

5.  Protective effects of 5-HT1A receptor agonists against emotional changes produced by stress stimuli are related to their neuroendocrine effects.

Authors:  M Tsuji; H Takeda; T Matsumiya
Journal:  Br J Pharmacol       Date:  2001-10       Impact factor: 8.739

6.  Role of maternal 5-HT(1A) receptor in programming offspring emotional and physical development.

Authors:  A van Velzen; M Toth
Journal:  Genes Brain Behav       Date:  2010-11       Impact factor: 3.449

7.  Agonist-induced internalization of serotonin-1a receptors in the dorsal raphe nucleus (autoreceptors) but not hippocampus (heteroreceptors).

Authors:  M Riad; K C Watkins; E Doucet; M Hamon; L Descarries
Journal:  J Neurosci       Date:  2001-11-01       Impact factor: 6.167

8.  Possible antidepressant dihydroergosine preferentially binds to 5-HT1B receptor sites in the rat hippocampus.

Authors:  D Muck-Seler; D Pericić
Journal:  J Neural Transm Gen Sect       Date:  1993

9.  5-HT1A receptor-effector system responsivity in panic disorder.

Authors:  K P Lesch; M Wiesmann; A Hoh; T Müller; J Disselkamp-Tietze; M Osterheider; H M Schulte
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530
  9 in total

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